[Condition of the nervous elements of skeletal muscle in Duchenne myopathy].

Zh Nevropatol Psikhiatr Im S S Korsakova

Published: September 1976

In order to determine the role of the nervous system in the pathogenesis of myopathy, the author examined the nervous apparatus in a bioptate of the widest muscle of the back in 8 patients with Duchenne's myopathy and in some other muscles in one post-mortem case of the same disease. The morphological changes in the nervous structures of skeletal muscles were expressed in signs of irritation, substituted by destruction which began in the terminal parts and was more expressed in the atrophized muscles. Besides there were symptoms of excessive growth of the nervous filaments especially in the initial phases of the process. The regenerating nervous filaments are subjected to destruction and do not provide an innervation of the muscles.

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