AI Article Synopsis
- Two monthly studies in May and October 1994 analyzed the susceptibility of Streptococcus pyogenes to penicillin and erythromycin across 58 centers in 27 Argentine cities.
- A total of 1,072 isolates were tested using diffusion methods, and 595 of those were also assessed by agar dilution, with no instances of penicillin-resistant strains found (MIC100 = 0.03 microgram/ml).
- Only four strains showed erythromycin resistance (0.14% in May and 0.28% in October), with three having an inducible resistance mechanism and one displaying a different resistance phenotype.
Article Abstract
Two monthly studies on the prevalence of penicillin and erythromycin susceptibility of Streptococcus pyogenes were performed in May and October of 1994 in Argentina. A total of 58 centers from 27 cities participated in these studies. A total of 1072 isolates were tested by a diffusion method, although 595 isolates were tested both by the diffusion and an agar dilution method (n = 1767 isolates). No penicillin-resistant streptococci were found in our study (MIC100 = 0.03 microgram/ml). Only four isolates were confirmed as erythromycin resistant S. pyogenes (prevalence 0.14 and 0.28% in May and October 1994, respectively). Resistance in three isolates was due to an inducible mechanism, although in one strain a different phenotype was observed.
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| http://dx.doi.org/10.1016/s0732-8893(97)00070-9 | DOI Listing |
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