The suppressive action of a magnet-laser ray and electrolyzed sodium hypochlorite solution on the persistence factors (antilysozyme, "anti-interferon") of Staphylococcus aureus and Neisseria gonorrhoeae is shown. The optimum conditions (time, dose, concentration) for the regulation of the persistence properties of the pathogens has been determined. The use of physicochemical factors in the proposed parameters has been shown to be effective for the therapy of purulent inflammatory diseases and the sanitation of S.aureus carriers.

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