Background: Epidemiologic and experimental data suggest that estrogen has a salutary effect on Trichomonas vaginalis.

Case: A metronidazole-allergic postmenopausal woman was cured of vaginal trichomoniasis in association with discontinuation of estrogen replacement therapy.

Conclusion: Hormonal manipulation should be studied for the management of women with trichomoniasis who are allergic to metronidazole or who are infected with metronidazole-resistant strains of Trichomonas vaginalis.

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http://dx.doi.org/10.1097/00007435-199710000-00009DOI Listing

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