In 45% of 212 cases of diphtheria toxica in adults heart complications were observed. The earliest ECG signs are sinus bradycardia, AV dissociation, AV escape rhythms, prolongation of QT interval, high U wave (U > T, T + U wave). In the cases where differential diagnosis of myocarditis and other heart diseases in adults is difficult, the attention must be focused on the sickle-like depression ("sagging") of ST-interval that is a typical sign in diphtheric myocarditis. The most severe forms of diphtheric myocarditis are complicated by AV and intraventricular conduction disturbances and malignant ventricular arrhythmias.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
High mortality diphtheritic myocarditis with conduction disturbance, case series, and review of literature.
Ann Med Surg (Lond)
August 2023
Manamohan Cardiovascular Thoracic and Transplant Centre, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu.
Unlabelled: Diphtheria cases are still being reported in various parts of the globe. Although complete heart block resulting from diphtheric myocarditis is infrequent, it can lead to fatality. Awareness and recognition of this help strengthen the importance of vaccines and their proper management.
View Article and Find Full Text PDFComplete heart block due to diphtheritic myocarditis in the present era.
Ann Pediatr Cardiol
January 2013
Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Diphtheria continues to be reported from many parts of the world. Complete heart block is rare but often fatal complication of diphtheric myocarditis. We report six children with diphtheric myocarditis who presented with complete heart block.
View Article and Find Full Text PDFCardiac troponins are highly specific markers of myocardial injury. It has been suggested that, unlike other markers of myocardial injury, troponins could be released in reversible myocardial injury and the myocardial necrosis does not have to occur for troponins to be released from myocytes. Reversibly injury related changes in myocyte membrane are considered sufficient for the release of cardiac troponins from the free cytosolic pool, whereas in case of irreversible myocardial injury the source of troponin release is the structural damage of the myocytes.
View Article and Find Full Text PDFThe authors of the article consider the issue of employment of some treatment options for the grave forms of diphtheria and complications thereof in adult subjects to be a matter of debate and they report their experience gained with the use of rarely employed but efficient means of remediation. In diphtherial myocarditis concurrent with acute renal failure with a critical uncorrectable decline in myocardial contractility in spite of a progressive necrosis of the renal parenchyma due to an inadequate perfusion and toxic nephrosis an adrenomimetic drug (depamine) is to be prescribed. A ban on administration of glycosides is not to be regarded as a dogma.
View Article and Find Full Text PDFExamination of 159 diphtheria patients diagnosed myocarditis in 64 of them. The latter were divided into 3 groups: with mild, moderate and severe myocarditis. The patients with and without diphtheria have undergone two-dimensional echocardiography with estimation of the asinergia index (AI) and left ventricular (LV) ejection fraction.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!