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Retrospective registry-based nationwide analysis of the COVID-19 lockdown effect on the volume of general and visceral non-malignant surgical procedures.
Surg Pract Sci
June 2024
Division of Trauma Surgery, Department of Traumatology, University Hospital Zurich, University Zurich, Switzerland.
Introduction: Coronavirus disease 2019 (COVID-19) is an acute virus infection, which was declared a pandemic by the World Health Organization. The Swiss government decreed a public lockdown to reduce and restrict further infections. The aim of this investigation was to analyze the impact of the first COVID-19 lockdown on the performance of general and visceral surgery procedures.
View Article and Find Full Text PDFA Study of the Comparison Between Preoperative Ultrasonography Findings With Intraoperative Observations in Laparoscopic Cholecystectomy.
Cureus
December 2024
General Surgery, Dr. Dnyandeo Yashwantrao Patil Medical College, Hospital and Research Centre, Dr. Dnyandeo Yashwantrao Patil Vidyapeeth (Deemed to be University), Pune, IND.
Aim: This study aims to evaluate the accuracy of ultrasonography (US) by comparing preoperative ultrasonographic findings with intraoperative observations during laparoscopic cholecystectomy (LC).
Materials And Methods: An observational analytical study was conducted at a tertiary hospital in Pune over two years and included 98 patients aged 20-80 with symptomatic cholelithiasis confirmed by US. Preoperative parameters assessed included gallstone number, gallbladder volume, wall thickness, and pericholecystic fluid.
Metabolic dysfunction-associated liver disease and biliary lithiasis in children with Down Syndrome: a retrospective study.
Rev Paul Pediatr
January 2025
Universidade Federal do Paraná, Curitiba, PR, Brazil.
Objective: To investigate the presence of metabolic dysfunction-associated fatty liver disease (MAFLD) and gallbladder abnormalities in a sample of people with Down syndrome in Brazil.
Methods: This is a retrospective study using medical charts involving Down syndrome patients, diagnosed by karyotype, aged over 5 years, who underwent abdominal ultrasound and were monitored by the same professional in a clinic in Curitiba, Brazil. Data spanned January 1995 to September 2023; all cases with no use of alcohol or hepatotoxic medications.
Whole Transcriptome-Wide Analysis Combined with Summarydata-Based Mendelian Randomization Identifies High-Riskgenes for Cholelithiasis Incidence.
Clin Transl Gastroenterol
January 2025
Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang province, China.
Background: Cholelithiasis is influenced by various factors, including genetic elements identified in genome-wide association studies (GWAS), but their biological functions are not fully understood.
Methods: Analyzing data from the Finngen database with 37,041 cholelithiasis cases and 330,903 controls, this study combined SNP data from GTEx v8 and linkage disequilibrium data from the 1000 Genomes Project. Using the TWAS FUSION protocol and SMR analysis, it investigated the relationship between gene expression and cholelithiasis, employing colocalization tests and conditional analyses to explore causality.
Age-stratified trends and outcomes of inpatient cholecystectomy for acute cholecystitis in the United States.
Surg Open Sci
January 2025
Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Background: The elderly population in the United States is rapidly expanding. Older patients over age 65 with acute cholecystitis may face greater perioperative risk compared to younger patients undergoing urgent laparoscopic cholecystectomy. We aimed to characterize trends in utilization and outcomes of inpatient cholecystectomy across the United States stratified by age.
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