Purpose: To compare commercially available 14-guage core biopsy guns and 11- and 14-gauge, directional, vaccum-assisted biopsy probes for tissue yield and fragmentation.
Materials And Methods: One hundred passes were made through fresh turkey breasts by using each of 11 14-gauge, automated biopsy gun-needle combinations and a directional, stereotactic, vacuum-assisted biopsy system equipped with 11- or 14-gauge probes. Specimens were measured for total weight, individual length, diameter, and number of fragments.
Results: Among the handheld devices, the Pro-Mag 2.2 gun (Manan Medical Products, Northbrook, Ill) and 14-gauge Biopsy-Cut needle (Bard, Covington, Ga) had the greatest yield (17.7 mg per core specimen); this combination also produced the greatest percentage of nonfragmented cores (83%). Directional, vacuum-assisted biopsy specimens were significantly larger (P < .001): 36.8 mg per core specimen for the 14-gauge probe and 94.4 mg per core specimen for the 11-gauge probe. Specimens obtained with directional, vacuum-assisted biopsy were more fragmented than those obtained with spring-actuated, two-stage, long-throw, automated biopsy systems.
Conclusion: Statistically significant differences with various biopsy devices are seen in the breast tissue yield and in fragmentation.
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http://dx.doi.org/10.1148/radiology.205.1.9314986 | DOI Listing |
J Pers Med
January 2025
Multidisciplinary Breast Centre, Department of Women's and Children's Health Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
B3 breast lesions, classified as lesions of uncertain malignant potential, present a significant diagnostic and therapeutic challenge due to their heterogeneous nature and variable risk of progression to malignancy. These lesions, which include atypical ductal hyperplasia (ADH), papillary lesions (PLs), flat epithelial atypia (FEA), radial scars (RSs), lobular neoplasia (LN), and phyllodes tumors (PTs), occupy a "grey zone" between benign and malignant pathologies, making their management complex and often controversial. This article explores the diagnostic difficulties associated with B3 lesions, focusing on the limitations of current imaging techniques, including mammography, ultrasound, and magnetic resonance imaging (MRI), as well as the challenges in histopathological interpretation.
View Article and Find Full Text PDFRadiol Oncol
January 2025
1Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern,
Background: The study aimed to investigate the reduction of hematoma risk during MRI-guided breast biopsies by evaluating position-dependent intervention parameters and characteristics of the target lesion.
Materials And Methods: We retrospectively analyzed 252 percutaneous MRI-guided breast biopsies performed at a single center between January 2013 and December 2023. Two groups were built depending on the severity of relative hematoma formation (using a cut-off ≤ 7.
Quant Imaging Med Surg
January 2025
Department of Radiology, Changi General Hospital, Singapore, Singapore.
Percutaneous biopsy is the standard of care for breast lesions, except nipple lesions which are primarily biopsied by excision due to perceived risks of pain and bleeding. However, excisional biopsy of nipple lesion inevitably leads to disfigurement and possible loss of the nipple-areolar complex (NAC), highlighting the need for minimally invasive biopsy techniques. We present our experience of seven patients who underwent ultrasound-guided core biopsy or vacuum-assisted biopsy (VAB) for sampling of clinically occult nipple lesions.
View Article and Find Full Text PDFJ Clin Med
December 2024
Multidisciplinary Breast Centre, Dipartimento Scienze della Salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
: B3 breast lesions, characterized by uncertain malignant potential, pose a significant challenge for clinicians. With the increasing use of preoperative biopsies, there is a need for careful management strategies, including watchful waiting, vacuum-assisted excision (VAE), and surgery. This study aims to assess the concordance between preoperative biopsy findings and postoperative histology, with a focus on evaluating the positive predictive value (PPV) for malignancy in B3 lesions.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Breast Surgery, Mindong Hospital Affiliated to Fujian Medical University, No. 89, Heshan Road, Fu'an, 355000, Fujian Province, China.
Granulomatous mastitis (GM) poses challenges in diagnosis and treatment due to its similarities with other breast diseases like cancer. The comparative study evaluated the efficacy and safety of a vacuum-assisted biopsy device with minimally invasive excisions compared to traditional wide local excisions. The vacuum-assisted biopsy device technique offers benefits such as precise tissue removal, reduced damage to healthy tissue, shorter surgery and recovery times, and lower postoperative complication risks.
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