AI Article Synopsis
- Pyoderma gangrenosum is linked to myelogenous leukemia and plasma cell disorders, showing a unique appearance with an advancing bullous margin when paired with leukemia.
- The cause of this skin condition remains unclear, but it may involve issues with the immune system.
- There is a recognized association of pyoderma gangrenosum occurring alongside agnogenic myeloid metaplasia in patients.
Article Abstract
Pyoderma gangrenosum has been associated with myelogenous leukemia and plasma cell dyscrasia. When associated with leukemia, pyoderma gangrenosum often has a distinctive clinical presentation with an advancing bullous margin. The pathogenesis of this disorder is unknown, although defective immune mechanisms may be operative. The occurrence of pyoderma gangrenosum and agnogenic myeloid metaplasia in the same patient has now been reported sufficiently to make it a recognized association.
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