Francisco Romero, a Catalonian physician, became the first heart surgeon when he performed an open pericardiostomy to treat a pericardial effusion in 1801. He presented his work at the Society of the School of Medicine in Paris in 1815, but the procedure was considered too aggressive and his work was silenced for many years. Proper credit should be given to Romero as the first man who directly approached the heart by incising the pericardium.
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http://dx.doi.org/10.1016/s0003-4975(97)00760-1 | DOI Listing |
ACS Appl Electron Mater
December 2024
Department of Electronics and Computer Science, University of Granada, Granada 18071, Spain.
In the evolution of pervasive electronics, it is imperative to significantly reduce the energy consumption of power systems and embrace sustainable materials and fabrication processes with minimal carbon footprint. Within this context, thermoelectric generators (TEGs) have garnered substantial attention in recent years because of the readily available thermal gradients in the environment, making them a promising energy-harvesting technology. Current commercial room-temperature thermoelectrics are based on scarce, expensive, and/or toxic V-VI chalcogenide materials, which limit their widespread use.
View Article and Find Full Text PDFMed Image Anal
January 2025
MedICAL Laboratory, Polytechnique Montréal, Montreal, Canada; Centre de recherche du CHUM (CRCHUM), Montreal, Canada; Université de Montréal, Montreal, Canada.
Colorectal liver metastases (CLM) affect almost half of all colon cancer patients and the response to systemic chemotherapy plays a crucial role in patient survival. While oncologists typically use tumor grading scores, such as tumor regression grade (TRG), to establish an accurate prognosis on patient outcomes, including overall survival (OS) and time-to-recurrence (TTR), these traditional methods have several limitations. They are subjective, time-consuming, and require extensive expertise, which limits their scalability and reliability.
View Article and Find Full Text PDFiScience
July 2024
Institute of Cancer and Genomic Sciences, Birmingham Centre for Genome Biology, University of Birmingham, Birmingham, UK.
To ensure timely duplication of the entire eukaryotic genome, thousands of replication machineries (replisomes) act on genomic DNA at any time during S phase. In the final stages of this process, replisomes are unloaded from chromatin. Unloading is driven by polyubiquitylation of MCM7, a subunit of the terminated replicative helicase, and processed by p97/VCP segregase.
View Article and Find Full Text PDFPolymers (Basel)
June 2024
Departamento de Ingeniería de Procesos, Universidad de Las Palmas de Gran Canaria, Edificio de Fabricación Integrada, Parque Científico-Tecnológico de la ULPGC, Campus Universitario de Tafira Baja, 35017 Las Palmas de Gran Canaria, Las Palmas, Spain.
The wide range of applications and the numerous advantages of plastics have led to their excessive use, with subsequent damage to ecosystems. As an environmentally friendly alternative, biocomposites have gained much attention, and microalgae have become a potential source for their production. In this study, the use of washed and unwashed Spirulina in polyethylene-based composites has been evaluated as a way to prevent the thermooxidation of polyethylene, while at the same time, reducing the amount of virgin plastic used.
View Article and Find Full Text PDFVaccine
September 2024
Instituto de Agrobiotecnología (IdAB; CSIC-Gobierno de Navarra), Avda. Pamplona 123, 31192 Mutilva, Navarra, Spain. Electronic address:
Small ruminants affected by brucellosis, caused mainly by Brucella melitensis and B. ovis, suffer reproductive disorders, leading to significant economic losses worldwide. Vaccination is an essential tool to prevent the disease in ovine and caprine livestock, but the only vaccine recommended to date is B.
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