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The MIR181A2HG/miR-5680/VCAN-CD44 Axis Regulates Gastric Cancer Lymph Node Metastasis by Promoting M2 Macrophage Polarization.
Cancer Med
January 2025
Department of Gastrointestinal Surgery, Affiliated Hospital and Medical School of Nantong University, Nantong, China.
Background: Lymphatic metastasis in gastric cancer (GC) profoundly influences its prognosis, but the precise mechanism remains elusive. In this study, we identified the long noncoding RNA MIR181A2HG as being upregulated in GC and associated with LNs metastasis and prognosis.
Methods: The expression of MIR181A2HG in GC was identified through bioinformatics screening analysis and qRT-PCR validation.
Industry affiliation influence on randomized controlled trials for platelet-rich plasma in the treatment of lateral epicondylitis: a systematic review.
JSES Int
November 2024
Department of Orthopaedic Surgery, University of Southern California Keck School of Medicine Los Angeles, Los Angeles, CA, USA.
Background: Explicit funding and industry affiliation are believed to potentially impact medical research. There have been an increasing number of studies that have evaluated this relationship. The purpose of this study is to determine whether industry affiliation influences the outcomes of randomized controlled trials that investigate the effectiveness of platelet-rich plasma (PRP) in the treatment of lateral epicondylitis.
View Article and Find Full Text PDFThe clinical course and outcomes following arthroscopic frozen shoulder 360° release.
JSES Int
November 2024
Queensland Unit for Advanced Shoulder Research (QUASR), Queensland University of Technology, Brisbane, Australia.
Background: Frozen shoulder (FS) is a debilitating inflammatory condition affecting the shoulder capsule that causes significant pain and stiffness. Its etiology, pathophysiology, and treatment remain poorly understood. Although regarded as self-limiting, FS can have profound implications on the activities of daily living and usually takes 1-4 years to resolve on its own accord.
View Article and Find Full Text PDFCortical windows for implant and cement removal during revision total elbow arthroplasty.
JSES Int
November 2024
Division of Hand and Upper-Extremity Surgery, Department of Orthopaedic Surgery, Geisinger Commonwealth School of Medicine, Geisinger MSKI, Danville, PA, USA.
Background: Revision total elbow arthroplasty (rTEA) remains a technically challenging procedure with potential for substantial morbidity. Cases involving excessively long cement mantles, removal of well-fixed implants or infected revisions requiring complete cement removal introduce additional technical challenges. Our purpose was to describe the outcomes, results, and complications associated with the use of cortical windows in rTEA.
View Article and Find Full Text PDFMaintained transparency of preserved cornea after penetrating keratoplasty for fungal keratitis: A case report.
Am J Ophthalmol Case Rep
December 2024
Department of Ophthalmology, University of Tokyo Hospital, 7-3-1, Bunkyo-ku, Tokyo, Japan.
Purpose: This report presents a case of fungal keratitis treated with penetrating keratoplasty using a cryopreserved cornea, highlighting the successful maintenance of corneal transparency post infection resolution.
Observations: A 57-year-old man complaining of pain in the right eye was referred to our hospital. Although diagnosed with fungal keratitis, his corneal scraping indicated the presence of , and he was unresponsive to voriconazole, micafungin, and pimaricin treatments.
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