Brain masses diagnosed in 47 pet dogs as tumors by CT scans, and confirmed in 12 dogs by necropsies, were injected with iodinated contrast media and treated by a modified CT scanner, the CTRx. Twenty-six dogs that received six or more weekly treatments of about 5.6 Gy per fraction, of which about 25% was contributed by radiation from the iodine, for a median total dose of 39 Gy, had a median survival of 230 days. This compares well with the 150 days reported for 25 dogs given 46-48 Gy of cobalt-60 radiation to the whole brain, and is significantly greater than the 6 to 13 days in untreated historic controls.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/(SICI)1520-6823(1997)5:1<8::AID-ROI2>3.0.CO;2-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers.
Arch Endocrinol Metab
January 2025
Henry Ford Health Hermelin Brain Tumor Center Department of Neurosurgery DetroitMI USA Henry Ford Health, Omics Laboratory, Hermelin Brain Tumor Center, Department of Neurosurgery, Detroit, MI, USA.
The aim of this study is to describe the management and evolution of a patient with the rare condition of double lactotroph tumors and assess the role of intraoperative ultrasonography (IOUS) for their detection and methylation-based liquid biopsy for their diagnosis and monitoring. A 29-year-old woman diagnosed with double lactotroph tumors through hormonal and MRI workup underwent surgical resection due to cabergoline intolerance. To detect a tumor missing through visual inspection, IOUS was performed.
View Article and Find Full Text PDFPapillary Tumor of the Pineal Region Treated With Surgery and Postoperative Radiotherapy: A Case Report.
Cureus
January 2025
Radiation Oncology, Centre Hospitalier Affilié Universitaire Régional, Trois-Rivieres, CAN.
Papillary tumors of the pineal region (PTPR) are extremely rare malignancies that make up less than 0.1% of primary brain tumors. They are usually treated with surgery and adjuvant tumor bed radiotherapy (RT).
View Article and Find Full Text PDFPerianal mass as the debut of metastatic pulmonary neoplasia.
Rev Esp Enferm Dig
January 2025
General and Digestive Surgery. Coloproctology Unit, Hospital Universitario Donostia.
A 56-year-old male smoker presented to the Emergency Department with a painful mass in the left ischiorectal fossa, which had been present for 2 months without any other symptoms. On examination, a hard, violet-colored mass was observed, with an ulcerated central area. Blood tests were normal, and the abdominal-pelvic CT scan showed multiple hypervascular intra-abdominal masses and soft tissue lesions.
View Article and Find Full Text PDFPotential of soybean-velvet bean combination tempe in improving cognitive function.
Narra J
December 2024
Department of Nutrition, Faculty of Medicine Science, Universitas Brawijaya, Malang, Indonesia.
Velvet bean is a native Indonesian legume containing L-dopa, yet it remains underutilized. The aim of this study was to analyze the effects of different types of tempe (soybean, velvet bean, and their combination) on cognitive function, brain histology, dopamine levels, and serum β-amyloid in rats, as well as to identify the parameters most influencing cognitive function, including brain mass and volume, hippocampal neuron count, and dopamine and β-amyloid levels. An experimental study was conducted using a completely randomized design with one factor: the protein source of diet.
View Article and Find Full Text PDFDetection of HTTex1p by western blot and immunostaining of HD human and mouse brain using neo-epitope antibody P90 highlights impact of CAG repeat expansion on its size, solubility, and response to MSH3 silencing.
bioRxiv
January 2025
Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129.
has been identified in human and mouse HD brain as the pathogenic exon 1 mRNA generated from aberrant splicing between exon 1 and 2 that contributes to aggregate formation and neuronal dysfunction (Sathasivam et al., 2013). Detection of the HTT exon 1 protein (HTTex1p) has been accomplished with surrogate antibodies in fluorescence-based reporter assays (MSD, HTRF), and immunoprecipitation assays, in HD postmortem cerebellum and knock-in mice but direct detection by SDS-PAGE and western blot assay has been lacking.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!