AI Article Synopsis
- Since the mid-1980s, scabies in HIV-infected individuals presents differently and is tougher to treat compared to those with healthy immune systems.
- Oral ivermectin is generally safe and effective, with a single dose often curing scabies in healthy individuals, but multiple doses may be necessary for those with HIV.
- Crusted scabies in HIV patients requires a combination treatment approach, including oral ivermectin, 5% permethrin cream, and keratolytic agents to effectively manage the condition.
Article Abstract
Since the mid-1980s, worldwide reports confirm that scabies in individuals infected with the human immunodeficiency virus (HIV) result in a wide range of-clinical manifestations which differ from those seen in immunocompetent patients. There is also general agreement that HIV-related scabies is more difficult to treat. Oral ivermectin has been shown in several countries to be a safe and effective therapy. In otherwise healthy persons, one dose of 200 microg/kg is usually curative. In HIV-related scabies, one treatment may be curative but repeated doses may be required. Crusted scabies in these individual requires a combination of oral ivermectin, total body treatments with 5% permethrin cream, and keratolytic agents to hasten removal of crusts.
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| http://dx.doi.org/10.1016/s1085-5629(97)80047-8 | DOI Listing |
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