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Diagnostic methods and protocols for rapid determination of methicillin resistance in Staphylococcus aureus bloodstream infections: a comparative analysis.
Eur J Clin Microbiol Infect Dis
January 2025
Microbiology and Virology Unit, University Hospital Città Della Salute E Della Scienza Di Torino, Turin, Italy.
Purpose: To evaluate diagnostic performance of four diagnostic methods for rapid determination of methicillin resistance in S. aureus positive blood cultures (BCs).
Methods: Clinical and spiked BCs were subjected to the evaluation of the following methods and protocols: a.
Tuning Ion Current Rectifying Nanopipettes for Sensitive Detection of Methicillin-Resistant .
Anal Chem
January 2025
School of Chemistry, University College Dublin, Belfield, Dublin D04 N2E5, Ireland.
Infectious diseases pose a growing challenge in healthcare, with the increasing rate of antimicrobial resistance limiting therapeutic options available for treatment. Rapid detection of infections at the earliest opportunity can significantly improve patient outcomes. In this report, ion current rectifying quartz nanopipettes with ca.
View Article and Find Full Text PDFClinical characteristics of acute epiphyseal osteomyelitis and acute metaphyseal osteomyelitis of long bones in children.
J Pediatr Orthop B
January 2025
Department of Orthopaedic Trauma Surgery, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Jinan, Shandong Province, China.
This study aimed to summarize the clinical characteristics of acute epiphyseal osteomyelitis and acute metaphyseal osteomyelitis of long bones in children. Data of 43 children with acute osteomyelitis of long bones diagnosed and treated from November 2017 to January 2021 were retrospectively analyzed. Medical records, laboratory results, and MRI were reviewed.
View Article and Find Full Text PDFNanobubble Ozone Stored in Hyaluronic Acid-Decorated Liposome Solutions: Inactivating Antibiotic-Resistant Bacteria and Genotoxicity, Sub-Acute and Sub-Chronic Toxicity Tests.
Infect Drug Resist
January 2025
Department of Medical Biochemistry, Faculty of Medicine, Bandırma Onyedi Eylül University, Bandırma/Balıkesir, Turkey.
Introduction: Nanobubble ozone stored in hyaluronic acid-decorated liposomes (patent application PCT/TR2022/050177) was used, and the Minimum Inhibitory Concentration (MIC) was found to be 1562 ppm. (patient isolate), (patient isolate), (MRSA) (ATCC12493), and (ATCC25922) bacteria, which are hospital-acquired and healthcare-associated infections, were used. A time-dependent efficacy study was conducted at 1600 ppm.
View Article and Find Full Text PDFEfficacy of Contezolid in the Treatment of Catheter-Related Bloodstream Infections Caused by Methicillin-Resistant in a Patient with Hepatorenal Syndrome and Acute Kidney Injury: A Case Report.
Infect Drug Resist
January 2025
Department of Infectious Disease, Changzheng Hospital, Navy Medical University, Shanghai, People's Republic of China.
The Hepatorenal Syndrome-Acute Kidney Injury (HRS-AKI) patients infected with methicillin-resistant (MRSA) urgently require safe and effective treatment options due to their compromised hepatic and renal functions, as well as thrombocytopenia resulting from hypersplenism. In our case, an HRS-AKI patient who underwent continuous renal replacement therapy for fluid overload developed fever with chills. His blood tests indicated elevated C-reactive protein and neutrophils, low platelet count, and bilateral lung infiltrates.
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