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Sub-Chronic 30 mg/kg Iron Treatment Induces Spatial Cognition Impairment and Brain Oxidative Stress in Wistar Rats.

Biol Trace Elem Res

January 2025

Laboratory Functional Physiology and Bio-Resources Valorisation, Higher Institute of Biotechnology of Beja, University of Jendouba, Avenue Habib Bourguiba BP 382, 9000, Beja, Tunisia.

Iron overload has been shown to have deleterious effects in the brain through the formation of reactive oxygen species, which ultimately may contribute to neurodegenerative disorders. Accordingly, rodent studies have indicated that systemic administration of iron produces excess iron in the brain and results in behavioral and cognitive deficits. To what extent cognitive abilities are affected and which neurobiological mechanisms underlie those deficits remain to be more fully characterized.

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Hyphopichia pseudoburtonii, is emerging as a potential biocontrol agent against various phytopathogens. These traits have been attributed to the production of various antifungal compounds in the presence of target pathogens. However, the broad molecular mechanisms involved in the antifungal activity are not yet understood.

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Vanadium-based oxides have garnered significant attention for aqueous zinc batteries (AZBs), whereas sluggish Zn diffusion and structural collapse remain major challenges in achieving high-performance cathodes. Herein, different structures of iron-vanadium oxides were fabricated by modulating the amount of vanadium content. It is found that the porous Mott-Schottky heterojunction composed of FeVO and FeVO mixed phase was used to construct a self-generated FeVO-5 structure, which could lower the diffusion barrier and improve the electron transport derived from the formed built-in electric field at the interface, showing faster reaction kinetics and improved capacity compared with the singe-phase FeVO-1.

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Protein hydrolysates derived from superworm (Zophobas morio): Composition, bioactivity, and techno-functional properties.

Int J Biol Macromol

January 2025

Laboratory of Food Technology, School of Chemistry and Food Engineering, Federal University of Rio Grande, FURG, Av. Itália, Km 08, 96203-900, Brazil; Graduate Program in Aquaculture, Federal University of Rio Grande - FURG, Av. Itália, Km 08, Rio Grande, RS 96201-900, Brazil.

This study aimed to produce protein hydrolysates from superworm (Zophobas morio) flour using the enzymes alcalase (HA), protamex (HP), or flavourzyme (HF), and to characterize their nutritional composition, techno-functional properties, bioactive capacity, and bioaccessibility index. The enzymatic process increased the total amino acid and crude protein contents of the hydrolysates by approximately 36 % and 46 %, respectively, generating better foaming capacity, oil retention, and emulsification capacity, when compared to raw flour. Although 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical capture was similar between the hydrolysates, HA (1479,66 μM FeSO/g) and HP (1514,66 μM FeSO/g) showed greater antimicrobial and iron reducing power (FRAP) activity, while HF has a higher scavenging efficiency for the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical (27.

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In Situ Balanced Synthesis of High-Activity Low-Spin Iron Cathode Prussian Blue for Enhanced Sodium-Ion Storage.

Nano Lett

January 2025

Key Laboratory of Advanced Structural Materials, Ministry of Education, and School of Materials Science and Engineering, Changchun University of Technology, Changchun 130012, China.

The growing market for sodium-ion batteries has stimulated interest in research on Prussian blue-type cathode materials. Iron hexacyanoferrate (FeHCF) is considered a desirable Prussian blue-type cathode, but the incomplete electrochemical property of its low-spin iron sites hinders its further practical application. In this paper, carboxymethyl cellulose is demonstrated to have an appropriate binding energy through DFT calculations, synthesize Prussian blue in situ, balance Fe and water in FeHCF, and introduce Fe vacancies to activate low-spin Fe sites.

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