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Genomic and metabolic characterization of isolated from domestic and wild animals.
Appl Environ Microbiol
December 2024
Microbiological Sciences Department, North Dakota State University, Fargo, North Dakota, USA.
Article Synopsis
- The bacterial pathogen, significant in both animals and humans, is linked to a variety of infections, highlighting the need to understand its genomic and metabolic features for effective control.
- Whole-genome sequencing and antimicrobial susceptibility testing were utilized to analyze 83 genomes from multiple animal hosts, revealing that the strains are not specific to hosts or body sites, indicating a broader infection potential.
- The study found conserved virulence genes and metabolic versatility in the pathogen, which may enhance its survival and competitiveness, raising concerns about its zoonotic potential and health impacts on humans and animals.
Managing Recurrent Endocarditis in Substance Use Disorder: The Role of Civil Commitment and Comprehensive Care.
Am J Case Rep
January 2025
Department of Behavioral Medicine and Psychiatry, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA.
BACKGROUND The incidence of drug-induced infectious endocarditis is rapidly rising in the United States. Healthcare providers face different challenges in the management of infectious endocarditis in persons who inject drugs, including addiction relapse, non-compliance with treatment, and the associated social stigma. These factors collectively complicate the management of drug-induced endocarditis, requiring comprehensive strategies that address both the medical condition and the underlying substance use disorder, as well as socio-behavioral aspects of patient care.
View Article and Find Full Text PDFWindsock mitral valve after prior aortic valve endocarditis.
J Cardiothorac Surg
December 2024
Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Background: Windsock deformities, though rare, represent a severe form of valvular aneurysm distinguished by localized balloon-like protrusions of the leaflet body. Here, we present a compelling case of windsock mitral valve (MV) formation subsequent to incompletely managed aortic valve (AV) endocarditis. The case is illustrated through radiographic, intraoperative, and histopathologic images.
View Article and Find Full Text PDFIron Deficiency Anemia as a Rare Presentation of Subacute Bacterial Endocarditis Caused by a Rare Organism.
Cureus
November 2024
General Internal Medicine, Luton and Dunstable University Hospital, Luton, GBR.
Infective endocarditis commonly presents with fever, malaise, fatigue, and chest pain. However, this case report details an atypical presentation of infective endocarditis when a 63-year-old male patient was referred by his general practitioner to the emergency department with shortness of breath and substantial weight loss to investigate his symptomatic anemia. His initial assessments revealed severe iron deficiency anemia without any gastrointestinal or any other source of bleeding.
View Article and Find Full Text PDFAcute Myocardial and Hemorrhagic Cerebral Infarction Secondary to Non-bacterial Thrombotic Endocarditis in a Patient with Advanced Uterine and Ovarian Cancer.
Intern Med
December 2024
Division of Cardiovascular Surgery, Oita Prefectural Hospital, Japan.
Non-bacterial thrombotic endocarditis (NBTE) causes myocardial and cerebral infarctions and is associated with advanced stages of malignancy. However, only a few cases of myocardial and cerebral infarctions have been reported in the same patient. We herein report a 47-year-old woman with advanced uterine and ovarian cancer who experienced acute myocardial infarction (MI) after receiving chemotherapeutic intervention for the cancer and hemorrhagic cerebral infarction 1 month after admission for acute MI, attributable to NBTE of the aortic valve.
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