Information protocols on the causes of acute poisoning exposures with chemicals in children up to 14 years old collected during 1990-95 at the National Poison Information Centre have been analyzed. Approximately 96% of intoxication were accidental, 44% of patients were poisoned with drugs, 22% with household products and 14% with pesticides. Almost 25% of drug poisonings were due to sedative and to psychotropic drugs, and 17% to drug mixtures. The frequency of mushrooms and plants poisonings were low - 6%. In Poland there are practically no acute poisoning departments which treat children (actually, there is only one Poison Unit in Kraków at Polish-American Children's Hospital), and thus these patients are treated in paediatric wards and paediatric hospitals, so complete data on the poisonings in children from over the whole territory of Poland are not available. However, we believe that the frequency of causes of children's intoxication in our country is properly reflected in our material. This allows us to draw conclusions of the prevention of poisoning in this age group.
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Clin Toxicol (Phila)
January 2025
National Poisons Information Service, Cardiff Unit, University Hospital Llandough, Penarth, UK.
Introduction: Ibogaine is a psychoactive alkaloid derived from the root bark of the West African shrub . It is not licensed in the United Kingdom but is used by individuals to alleviate drug or alcohol use.
Methods: A retrospective analysis of telephone enquiries involving ibogaine between 1 January 2012 and 31 December 2022 to the United Kingdom National Poisons Information Service was performed.
BMJ Open
January 2025
National Poison Centre, Universiti Sains Malaysia, Georgetown, Penang, Malaysia
Objective: Glyphosate is widely used in Malaysian agriculture but poses a significant under-reported public health concern due to poisoning. This paper aims to study the epidemiology of glyphosate poisoning in Malaysia, assessing severity, identifying risk factors, and high-risk groups.
Setting: All glyphosate-related data of the Malaysia National Poison Centre from 2006 to 2023.
Introduction Acute poisoning in children is still a global health concern that necessitates visiting the emergency department that might associated with morbidity and mortality. It has an impact on social, economic, and health issues, particularly for children under five who account for the majority of poisonings worldwide. Poisoning can result in mild cases, serious complications, or even death; oral ingestion is the most common way that poisoning occurs in children.
View Article and Find Full Text PDFIndian J Occup Environ Med
December 2024
Viral Research and Diagnostic Laboratory (VRDL), Government Medical College, Patiala, Punjab, India.
Pesticides induce oxidative DNA damage and genotoxic effects such as DNA single-strand breaks (SSBs), double-strand breaks (DSBs), DNA adducts, chromosomal aberrations, and enhanced sister chromatid exchanges. Such DNA damage can be repaired by DNA repair mechanisms. In humans, single nucleotide polymorphisms (SNPs) are present in DNA repair genes involved in base excision repair (BER) (, and nucleotide excision repair (NER) (, , , and ), and double-strand break repair (DSBR) ( and ).
View Article and Find Full Text PDFInt J Environ Health Res
January 2025
School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, China.
Myocardial infarction (MI) ranks as one of the primary causes of global disabilities and disease deaths. The association between fine particulate matter (PM2.5) and MI has gained attention in recent years.
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