Purpose: To evaluate the detectability of acute middle cerebral artery (MCA) infarctions by CT with regard to the time interval after symptom onset and to the infarction size. Analysis of the chronological appearance of signs of ischaemia.
Material And Methods: Two examiners retrospectively and independently evaluated CT scans from 171 patients with acute MCA infarctions performed within 24 hours after onset of symptoms.
Results: 92, respectively 87% of the Infarctions were correctly diagnosed. The detection rate did not increase after the first hour after onset of symptoms. All MCA infarctions involving the lentiform nucleus, but only 83% of the infarctions covering < 33% of the MCA area, were recognised. The hyperdense middle cerebral artery sign (HMCA5) was present in 75% of the infarctions in the first 90 minutes and in 15% from hour 12 to 24. Hypodensity of the lentiform nucleus appeared within 150 minutes, hypodensity of the convexity cortex at the earliest 60 minutes after onset of symptoms.
Conclusions: The detection rate of acute MCA infarctions corresponds with the infarction size, but does not significantly change after the first hour after symptom onset.
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http://dx.doi.org/10.1055/s-2007-1015467 | DOI Listing |
Neurol Med Chir (Tokyo)
January 2025
Department of Neurosurgery, Tohoku University Graduate School of Medicine.
Pediatric patients with moyamoya disease frequently show rapid progression with a high risk of stroke. Indirect revascularization is widely accepted as a surgical treatment for pediatric moyamoya disease, but it does not augment cerebral blood flow immediately, which leaves patients at risk for stroke peri-operatively. This delay in flow augmentation may make adding direct bypass the better option.
View Article and Find Full Text PDFWorld Neurosurg
January 2025
Department of Neurological Surgery, University of Louisville, Louisville, KY, USA. Electronic address:
Aneurysms of the middle cerebral artery (MCA) account for up to 40% of all unruptured intracranial aneurysms [1-3] and 14% to 20% of ruptured ones. [4-5] Giant MCA aneurysms are rare, representing 10% of cases [6], but carry an aggressive natural history, with the UCAS Japan study reporting an annual rupture rate of ∼ 17%. [7].
View Article and Find Full Text PDFAnn Neurosci
October 2024
Department of Radiology, Aga Khan University Hospital, Stadium Road, Karachi, Pakistan.
Background: Hyperdense middle cerebral artery sign (HMCAS) on a non-enhanced multidetector computed tomography (MDCT) scan is considered an important radiological marker in detecting acute arterial thrombotic occlusion, and it is one of the earliest signs of ischemic cerebrovascular accident (CVA). This finding has been observed within 90 min of symptom onset. Modern approaches to patients with cerebral infarction emphasize early diagnosis and management.
View Article and Find Full Text PDFJ Vis Exp
January 2025
Department of Physiology, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University;
Stroke is a leading cause of death and disability worldwide. Most cases of stroke are ischemic and result from the occlusion of the middle cerebral artery (MCA). Current pharmacological approaches for the treatment of ischemic stroke are limited; therefore, novel therapies providing effective neuroprotection against ischemic injury following stroke are urgently needed.
View Article and Find Full Text PDFBrain Sci
November 2024
State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing 400016, China.
Objectives: Cerebral edema, a prevalent consequence of brain injury, is associated with significant mortality and disability. Timely diagnosis and monitoring are crucial for patient prognosis. There is a pressing clinical demand for a real-time, non-invasive cerebral edema monitoring method.
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