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Absorption-Emission Codes for Atomic and Molecular Quantum Information Platforms.
Phys Rev Lett
December 2024
University of Maryland, NIST, Joint Center for Quantum Information and Computer Science, /, College Park, Maryland 20742, USA.
Diatomic molecular codes [V. V. Albert, J.
View Article and Find Full Text PDFA generalized structured coalescent for purifying selection without recombination.
Genetics
January 2025
Interfaculty Bioinformatics Unit, University of Bern, Bern 3012, Switzerland.
Purifying selection is a critical factor in shaping genetic diversity. Current theoretical models mostly address scenarios of either very weak or strong selection, leaving a significant gap in our knowledge. The effects of purifying selection on patterns of genomic diversity remain poorly understood when selection against deleterious mutations is weak to moderate, particularly when recombination is limited or absent.
View Article and Find Full Text PDFDenseSeg: joint learning for semantic segmentation and landmark detection using dense image-to-shape representation.
Int J Comput Assist Radiol Surg
January 2025
Medical Informatics, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Purpose: Semantic segmentation and landmark detection are fundamental tasks of medical image processing, facilitating further analysis of anatomical objects. Although deep learning-based pixel-wise classification has set a new-state-of-the-art for segmentation, it falls short in landmark detection, a strength of shape-based approaches.
Methods: In this work, we propose a dense image-to-shape representation that enables the joint learning of landmarks and semantic segmentation by employing a fully convolutional architecture.
Phenomenological Modeling of Antibody Response from Vaccine Strain Composition.
Antibodies (Basel)
January 2025
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
The elicitation of broadly neutralizing antibodies (bnAbs) is a major goal of vaccine design for highly mutable pathogens, such as influenza, HIV, and coronavirus. Although many rational vaccine design strategies for eliciting bnAbs have been devised, their efficacies need to be evaluated in preclinical animal models and in clinical trials. To improve outcomes for such vaccines, it would be useful to develop methods that can predict vaccine efficacies against arbitrary pathogen variants.
View Article and Find Full Text PDFRemedial, institutional or radical? Explaining community responses to violence against women in an NGO programme to prevent violence in Mumbai, India.
World Dev
July 2024
Society for Nutrition, Education and Health Action, Mumbai, India.
Despite ambitions in development and global health policy to transform communities into supportive environments for women facing risks of violence, our understanding of how to best engage communities remains incomplete. In particular, there is little evidence on the types of strategies that communities employ to address violence against women (VAW). We aimed to describe and analyse the processes involved in community responses to incidents of VAW in a non-governmental organisation (NGO) violence prevention programme in Mumbai, India.
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