Ultra rapid injection of isotonic sodium chloride after the injection of contrast medium may make it possible to clearly distinguish between the arterial phase and the portal phase. This method could improve the detectability of hepatocellular carcinoma on double phase dynamic spiral CT. A time-density analysis of the aorta and the portal vein was carried out according to the following 2 protocols (5 cases each). In protocol 1, 95 ml of Iopamidol (300 mgI/ml) was injected at a rate of 3 ml/second, while the protocol 2, 40 ml of isotonic sodium chloride was injected at a rate of 10 ml/second after the injection of 60 ml of Iopamidol (300 mgI/ ml) at a rate of 10 ml/second. The duration of the arterial phase (aortic enhancement unit (EU) > or = 200) in protocol 2 was 11 seconds, which was shorter than that in protocol 1. In protocol 2, the duration of the clearly portal dominant phase (reversal phase; aortic EU < portal EU) was about 11 seconds.
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