Objective: This study was carried out to determine whether ejaculation may modify the serum prostate-specific antigen (PSA) level and to investigate whether postejaculation serum PSA may play a role in male hypofertility work-up.
Methods: Serum PSA concentration was determined before and 1 h after ejaculation in 18 healthy men (group A) and in 16 men with male-factor infertility (group B). PSA change (delta) was recorded and analyzed.
Results: Postejaculation serum PSA differed significantly from basal levels (p = 0.0037 by the Wilcoxon signed rank test). Following ejaculation, a rise was noticed in 74% of subjects. The median relative change in PSA concentration was 54%. No difference in respect to mean, median and relative change was observed between study groups. In two cases (6%), PSA rose from normal level to more than 4 ng/ml.
Conclusion: A significant postejaculation serum PSA elevation does occur, it is thus recommended that men abstain from ejaculation for 24 h prior to PSA sampling. Postejaculation PSA was not found to significantly correlate with hypofertility.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
[Primary premature ejaculation of kidney deficiency and liver stagnation treated with warm acupuncture of large-quantity moxibustion: a randomized controlled trial].
Zhongguo Zhen Jiu
August 2024
Acupuncture and Moxibustion Department, Lianyungang Affiliated Hospital of Nanjing University of Chinese Medicine, Lianyungang 222004, Jiangsu Province, China.
Article Synopsis
- * 240 patients were divided into three groups: one receiving warm acupuncture, another receiving standard acupuncture without moxibustion, and a third group taking western medication (dapoxetine).
- * Results showed significant improvements in symptoms, including reduced duration of intercourse and enhanced overall sexual health indicators, across all treatment groups after 4 weeks of therapy.
Withania somnifera ameliorates sexual arousal and impotence in stressed sexually sluggish male rats by modulating neurotransmitters and NO/cGMP/PDE5α pathway.
J Ethnopharmacol
January 2024
Male Reproductive Physiology Lab., Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, UP, India. Electronic address:
Ethnopharmacological Relevance: Psychological stress is a growing global threat to male sexual potency and erection efficiency. Withania somnifera (L.) Dunal (WS), also known as Ashwagandha, is a well-known Ayurvedic herb.
View Article and Find Full Text PDFEjaculation Effect on Canine Prostatic Specific Esterase Serum Concentration.
Animals (Basel)
February 2020
Department of Veterinary Medicine (DiMeV), Section of Clinical Obstetrics, University of Bari "Aldo Moro", 70010 Valenzano, Italy.
Canine prostatic diseases are usually asymptomatic in their onset and often identified in advanced stages. Canine prostatic specific esterase (CPSE) represents an early serum marker for prostatic diseases, also in asymptomatic dogs. The present study aimed to identify the effects of ejaculation on serum CPSE.
View Article and Find Full Text PDFIdentification of capacitation inducers customized to sperm retrieved from inbred mouse epididymis.
Biochem Biophys Res Commun
June 2017
Division of Animal Resource Science, Kangwon National University, Chuncheon 24341, South Korea; Institute of Animal Resources, Kangwon National University, Chuncheon 24341, South Korea. Electronic address:
Acquisition of sperm capacitation post-ejaculation into the female reproductive tract is an essential step in the fertilization process. Accordingly, during in vitro fertilization, successful fertilization requires the induction of capacitation in epididymis-retrieved sperm. To date, many candidate substances have been considered as capacitation inducers; however, there are no reports on the efficiency of inducing sperm capacitation among the diverse inducers.
View Article and Find Full Text PDFReproductive function in male patients with type 1 diabetes mellitus.
Andrology
November 2015
Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
This study was undertaken to evaluate conventional and some of the main bio-functional spermatozoa parameters, serum gonadal hormones and didymo-epididymal ultrasound features in patients with type 1 diabetes mellitus (DM1). DM1 affects an increasing number of men of reproductive age. Diabetes may affect male reproduction by acting on the hypothalamic-pituitary-testicular axis, causing sexual dysfunction or disrupting male accessory gland function.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!