In the present study, besides a detailed clinical evaluation, roentgenographic changes in cardio-respiratory system in Indian soldiers (IS) during their 60 days stay at the arctic have been observed. These results have been compared with the responses at Delhi (before cold acclimatisation) and on return to Delhi (deacclimatisation). An attempt has also been made to compare the same physiological variables with those of Russian Migrants (RM) and Russian Natives (RN) in the arctic region to review significant differences if any. Heart Rate (HR) did not show much change; there was a tendency to increase in both systolic and diastolic blood pressure; and Kerdo's index inclined towards increased sympathetic activity in IS. X-ray chest (PA View) did not show any appreciable change in the lungs in the three groups. One subject amongst IS showed cardiac enlargement and RN subjects showed prominence of pulmonary artery and pulmonary vascular markings. All these physiological changes aim at increasing the cardiac output to overcome the ill effects of cold. Pneumopathy, a clinical condition of increased pulmonary haemodynamics could have resulted in the prominence of pulmonary artery and pulmonary blood flow in the RN. Most of the physiological changes reverted to the baseline value on return to Delhi thus proving that there were no permanent changes during short stay at extreme cold conditions.
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Health Qual Life Outcomes
January 2025
Department of Public Health, Research Unit for General Practice and Section of General Practice, University of Copenhagen, Copenhagen, Denmark.
Introduction: Validated patient-reported outcome measures (PROMs) are crucial for assessing patients' experiences in the healthcare system. Both clinically and theoretically, patient-centered consultations are essential in patient-care, and are often suggested as the optimal strategy in caring for patients with multimorbidity.
Aim: To either identify or develop and validate a patient-reported outcome measure (PROM) to assess patient-centredness in consultations for patients with multimorbidity in general practice.
Environ Microbiol
January 2025
Institute for Biological Sciences, Applied Ecology and Phycology, University Rostock, Rostock, Germany.
Streptofilum capillatum was recently described and immediately caught scientific attention, because it forms a phylogenetically deep branch in the streptophytes and is characterised by a unique cell coverage composed of piliform scales. Its phylogenetic position and taxonomic rank are still controversial discussed. In the present study, we isolated further strains of Streptofilum from biocrusts in sand dunes and Arctic tundra soil.
View Article and Find Full Text PDFThis case study of Kongsfjorden, western coastal Svalbard, provides insights on how freshwater runoff from marine- and land-terminating glaciers influences the biogeochemical cycles and distribution patterns of carbon, nutrients, and trace elements in an Arctic fjord system. We collected samples from the water column at stations along the fjord axis and proglacial river catchments, and analyzed concentrations of dissolved trace elements, together with dissolved nutrients, as well as alkalinity and dissolved inorganic carbon. Statistical tools were applied to identify and quantify biogeochemical processes within the fjord that govern the constituent distributions.
View Article and Find Full Text PDFMol Biol Rep
January 2025
International Degree Program of Animal Vaccine Technology, International College, National Pingtung University of Science and Technology, 1, Shuefu Road, Neipu, Pingtung, 91201, Taiwan.
Flagellin stimulates Toll-like receptor 5 (TLR5), triggering both innate and adaptive immune responses, making it a potential vaccine adjuvant. On mucosal surfaces, flagellin induces a strong release of cytokines, chemokines, and immunoglobulins. When used in its free monomeric form, flagellin has been shown to enhance immune responses when combined with vaccine antigens.
View Article and Find Full Text PDFBJGP Open
January 2025
The Research Unit for General Practice & Section for General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Background: In chronic care, patient-GP collaboration is essential, but might be challenging if patients have complex health problems due to multimorbidity, psychosocial predicaments and addiction problems. To understand and manage these challenges, it is important to explore how patients' and GPs' attempt to collaborate, to maintain and achieve an alliance in order to gain good quality of care.
Aim: To explore how dyads of GPs and patients that GPs deem have complex health problems and difficulties following treatment perceive and manage challenges in their chronic care partnership.
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