One hundred and ninety-two clinical specimens were used to compare the three chromogenic media Albicans ID, Candiselect, and CHROMagar Candida to a standard method using a Sabouraud-chloramphenicol agar medium and standard methods for identification of yeasts. The detection rates were 83.79, 83.24, 86.59 and 84.91% respectively. For the chromogenic media, the rates of direct identification (growth plus specific pigmentation) for Candida albicans were 56.50, 37.68 and 11.59% after 24 hours' incubation and 92.75, 91.30 and 88.57% after 72 hours' incubation respectively, with 100% specificity. Furthermore, CHROMagar Candida identified the five Candida tropicalis and the two Candida krusei strains detected after 48 hours' incubation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/BF02471913 | DOI Listing |
Alzheimers Dement
December 2024
UT Health San Antonio, San Antonio, TX, USA.
Background: Glycosylation is the most common post-translational modification in the brain. Aberrant glycosylation patterns are present in cerebrospinal fluid and brain tissue from Alzheimer's disease (AD) patients. Specifically, dysregulation of a particular form of terminal glycoconjugate modification, sialylation, has been identified in AD.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Background: Previous studies have found that mechanistic target of rapamycin complex 1 (mTORC1) activity is significantly increased in Alzheimer's disease (AD) patients and mouse models of AD. Additionally, inhibition of mTORC1 with systemic rapamycin treatment ameliorates AD-like phenotypes in several AD mouse models. However, the specific contribution of neuronal mTORC1 signaling in driving AD phenotypes has not yet been explored.
View Article and Find Full Text PDFEur J Dent
December 2024
Department of Oral Biology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Objective: Particulate matter 2.5 (PM2.5), an important air pollution particle, has been previously studied for its effects on various normal and cancer tissues.
View Article and Find Full Text PDFInt J Radiat Biol
January 2025
N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Moscow, Russia.
Background: Enumeration of residual DNA repair foci 24 hours or more after exposure to ionizing radiation (IR) is often used to assess the efficiency of DNA double-strand break repair. However, the relationship between the number of residual foci in irradiated cells and the radiation dose is still poorly understood. The aim of this work was to investigate the dose responses for residual DNA repair foci in normal human fibroblasts after X-ray exposure in the absorbed dose range from 0.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Molecular Medicine, Brain Signalling Laboratory, Institute of Basic Medical Sciences, Section for Physiology, University of Oslo, Oslo, Norway.
Propofol and ketamine are widely used general anaesthetics, but have different effects on consciousness: propofol gives a deeply unconscious state, with little or no dream reports, whereas vivid dreams are often reported after ketamine anaesthesia. Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist, while propofol is a γ-aminobutyric-acid (GABAA) receptor positive allosteric modulator, but these mechanisms do not fully explain how these drugs alter consciousness. Most previous in vitro studies of cellular mechanisms of anaesthetics have used brain slices or neurons in a nearly "comatose" state, because no "arousing" neuromodulators were added.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!