Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s001250051432 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Baseline characteristics including blood and urine metal levels in the Trial to Assess Chelation Therapy 2 (TACT2).
Am Heart J
July 2024
Department of Medicine at Mount Sinai Medical Center, Miami Beach, FL; Columbia University Division of Cardiology at Mount Sinai Medical Center, Miami Beach, FL.
Background: The reduction in cardiovascular disease (CVD) events with edetate disodium (EDTA) in the Trial to Assess Chelation Therapy (TACT) suggested that chelation of toxic metals might provide novel opportunities to reduce CVD in patients with diabetes. Lead and cadmium are vasculotoxic metals chelated by EDTA. We present baseline characteristics for participants in TACT2, a randomized, double-masked, placebo-controlled trial designed as a replication of the TACT trial limited to patients with diabetes.
View Article and Find Full Text PDFACQUIRED ECTOPIC POSTERIOR PITUITARY BRIGHT SPOT DUE TO VASCULOTOXIC SNAKEBITE.
AACE Clin Case Rep
May 2020
Department of Endocrinology, PGIMER, Chandigarh, India.
Objective: Vasculotoxic envenomation is an uncommon cause of hypopituitarism. Most described cases have varying extent of anterior pituitary dysfunction, but posterior pituitary involvement is extremely rare.
Methods: Clinical, biochemical, and radiologic evaluation of a young female who presented with secondary amenorrhea was performed.
Vasculotoxic effects of insulin and its role in atherosclerosis: what is the evidence?
Curr Atheroscler Rep
April 2011
University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
As a result of ambiguous results from several recent trials in diabetes, scrutiny has focused on the potential effects of insulin and its role in atherosclerosis. This article reviews the premise that anti-diabetes therapy (type 2 diabetes) with insulin causes vascular impairment that leads to atherothrombosis and compromises vascular integrity, which may further potentiates cardiovascular morbidity and mortality. Underlying mechanisms are discussed, including metabolic derangements (blood pressure, lipids, body weight, and glucose) and how these factors trigger insulin-like growth factor (IGF) receptors, leading to cancer.
View Article and Find Full Text PDFIs insulin vasculotoxic?
Diabetologia
July 1997
Department of Medicine, University College London Medical School, UK.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!