Under the Arctic Monitoring and Assessment Programme (AMAP), studies have been undertaken to compare potential fluxes of radiocaesium via important food products. The results for three Norwegian Arctic counties are presented in this paper. The comparative importance of different foodstuffs in contributing to collective dose varies spatially due to differing rates of production and transfer. Although reindeer meat is an important contributor to the radiocaesium flux following a nuclear release, other food products such as cow milk and lamb have been identified as potentially important. Assuming an even deposition following a nuclear release the radiocaesium flux was estimated to be highest for reindeer meat in Finnmark and Troms, whereas cow milk gave the highest flux in Nordland. The total number, geographical distribution and diet composition of indigenous peoples within different Arctic regions is an important factor affecting individual and collective doses arising from a nuclear release. Finnmark has been shown to be the most vulnerable of the three counties because it has the highest flux of radiocaesium and the largest number of indigenous people. The potential contribution of foodstuffs which are known to readily accumulate radiocaesium needs further consideration, in particular, mushrooms, freshwater fish and berries.
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http://dx.doi.org/10.1016/s0048-9697(97)00114-9 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Department of Chemistry, University of California, Berkeley, CA 94720.
Copper is an essential nutrient for sustaining vital cellular processes spanning respiration, metabolism, and proliferation. However, loss of copper homeostasis, particularly misregulation of loosely bound copper ions which are defined as the labile copper pool, occurs in major diseases such as cancer, where tumor growth and metastasis have a heightened requirement for this metal. To help decipher the role of copper in the etiology of cancer, we report a histochemical activity-based sensing approach that enables systematic, high-throughput profiling of labile copper status across many cell lines in parallel.
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Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China.
Sepsis is a serious and life-threatening condition, which can lead to organ failure and death clinically. Abnormally increased cell-free DNA (cfDNA) and inflammatory cytokines are involved in the development and progression of sepsis. Thus, cfDNA clearance and down-regulation of inflammatory factors are essential for the effective treatment of sepsis.
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December 2024
Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA), Laboratory of Hematology, University of Liège, Liège, Belgium.
Bispecific antibody is a new treatment for hematological disease, especially for lymphoma, myeloma and acute lymphoblastic leukemia. This class of treatment presents the same kind of side effect as CAR-T cell which are immune-mediated. Nevertheless, infectious complication remains a major concerns with related mortality.
View Article and Find Full Text PDFPhytomedicine
January 2025
Department of Integrative Biotechnology, and Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, Suwon 16419, Republic of Korea; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address:
Background: Inflammation is the body's innate reaction to foreign pathogens and serves as a self-regulating mechanism. However, the immune system can mistakenly target the body's own tissues, triggering unnecessary inflammation. For millennia, medicinal plants have been employed for the treatment of diseases.
View Article and Find Full Text PDFCell Death Dis
January 2025
School of Pharmacy, Faculty of Medicine & State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Small extracellular vesicles (sEVs), carrying PD-L1, have been implicated in immune evasion and tumor progression. However, understanding how PD-L1 sEVs are secreted still needs to be improved. We found that the secretion dynamics of PD-L1 sEVs is similar to that of other sEVs.
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