Results of the computer processing of the electron base of data of 1706 patients with duodenal ulcer are presented. The data base includes the pre- and postoperative findings of comprehensive clinical instrumental examinations of the patients. Special attention in the work was given to the diagnostic and prognostic significance of the gastric secretion parameters before operation (the nocturnal secretion. Key test). The main conclusion of the study is that the well-known prognostic criteria of the appearance of recurrent ulcers after vagotomy, based upon the findings of clinical instrumental examinations, the parameters of the acid gastric secretion included, are not sufficient. The level of acidity of the gastric juice in each patient is considered as a genetically fixed sign.

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