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Valvular Heart Disease-Related Mortality Between Middle- and High-Income Countries During 2000 to 2019.
JACC Adv
December 2024
Division of Cardiac Surgery, St. Michael's Hospital of Unity Health Toronto, Toronto, Ontario, Canada.
Background: Valvular heart disease (VHD) management has evolved rapidly in recent decades, but disparities in health care access persist among countries with varying socioeconomic backgrounds.
Objectives: The purpose of this study was to investigate global mortality trends from VHD and assess the difference between middle- and high-income countries.
Methods: We obtained mortality data from the World Health Organization Mortality Database for VHD and its subgroups (rheumatic valvular disease [RVD], infective endocarditis [IE], aortic stenosis [AS], and mitral regurgitation [MR]) from 2000 to 2019.
Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis.
Stem Cell Res Ther
January 2025
IRMB, Univ Montpellier, INSERM, CHU St Eloi, 80 AV A Fliche, 34295-Cedex-05, Montpellier, France.
Background: The regenerative potential of mesenchymal stromal/stem cells (MSCs) has been extensively studied in clinical trials in the past decade. However, despite the promising regenerative properties documented in preclinical studies, for instance in osteoarthritis (OA), the therapeutic translation of these results in patients has not been fully conclusive. One factor contributing to this therapeutic barrier could be the presence of senescent cells in OA joints.
View Article and Find Full Text PDFGeographical Distribution of Newly Accredited Anesthesiology Training Programs in Relation to Health Professional Shortage Areas and Medically Underserved Populations.
J Educ Perioper Med
January 2025
James Harvey Jones is an Assistant Clinical Professor in the Department of Anesthesiology at University of North Carolina in Chapel Hill, NC. Neal Fleming is a Professor of Clinical Anesthesiology in the Department of Anesthesiology and Pain Medicine at University of California Davis Medical Center in Sacramento, CA.
Background: Expanding the physician workforce in underserved areas is imperative for addressing healthcare disparities. The creation of new residency training programs has assisted in these efforts. However, anesthesiology training programs are infrequently studied in this regard.
View Article and Find Full Text PDFImproving 1-year liver allograft survival hazard ratios.
BMJ Open Qual
January 2025
Mayo Clinic, Rochester, Minnesota, USA.
Background: The Scientific Registry for Transplant Recipients (SRTR) publishes outcomes of all transplant centres in the USA two times a year. The outcomes are publicly available and used by insurance payers and patients to assess the performance of a programme. Poor performance can result in temporary suspension or termination of a transplant programme.
View Article and Find Full Text PDFTrends (2017-2022) in adolescent metabolic and bariatric surgery.
Surg Obes Relat Dis
December 2024
UMass Memorial Medical Center, Worcester, Massachusetts.
Article Synopsis
- Metabolic and Bariatric Surgery (MBS) for adolescents has been made more accessible due to recent policy changes, but challenges remain, particularly for diverse populations.
- A study from 2017-2022 revealed that about 15%-20% of MBS cases in the U.S. involved adolescents, predominantly females and white patients with an average age of 16.1 years.
- Despite a decline in cases during COVID-19, the volume rebounded, with an increase in sleeve gastrectomy and robotic-assisted surgeries, while overall complication rates remained low at 2.9%.
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