Blood rheology was compared in two groups of patients with ischemic heart disease (IHD). In group 1 patients low limbs were amputated. It is in them that rheological properties of blood were changed to the most extent. This is attributed to the effect of plasmic factors in the form of hypertriglyceridemia and hyperfibrinogenemia, sharp reduction of the total cross sectional vascular area (especially in high amputation) leading to blood cell damage associated with intensive platelet aggregation and red cell microhemolysis. Reduced muscular mass and resultant reduced capillary bed and deficiency of endothelial surface may stimulate accumulation of triglyceride-enriched very low density lipoproteins.
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