Background: Preoperative biometry for calculation of the refractive power of intraocular lenses is not sufficiently reliable in certain cases. Most frequently inaccuracies tend to occur in highly myopic eyes. Preceding refractive procedures can also impair IOL-calculation or even make it impossible.
Patients: In a highly myopic patient IOL-power calculation was not possible with conventional calculation formulas due to a preexisting refractive silicone lens located between the cataractuous natural lens and the iris. In another myopic patient ultrasound measurement of axial eye length produced variable and unreliable results. Therefore retinoscopy was performed intraoperatively in the aphakic eye. Refractive power of the IOL was calculated using a new formula. For validation of the method retinoscopy was performed intraoperatively in a second group of 11 patients with unproblematic ultrasound biometry.
Results: In 3 eyes IOL power was chosen according to intraoperative retinoscopy. A maximal deviation of 1.25 D from the aimed refraction resulted. In the second group, the retinoscopic method produced partially considerably inaccurate results as compared to the ultrasound biometry. Inaccuracies increased with the extent of hyperopia.
Conclusions: In cases of difficult or inaccurate preoperative ultrasound biometry IOL power can be estimated after intraoperative retinoscopy in the aphacic highly myopic eye. IOL power can be calculated instantly using computer programs or tables. This method additionally enables the surgeon to control the refractive result of intraocular lens implantation prior to wound closure. However this method lacks reliability in higher hyperopic eyes, as in these cases small changes in corneal vertex distance of the lens used for retinoscopy highly alter the result.
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http://dx.doi.org/10.1055/s-2008-1035043 | DOI Listing |
Hum Genet
January 2025
Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Refractive error (RE) and myopia are complex polygenic conditions with the majority of genome-wide associated genetic variants in non-exonic regions. Given this, and the onset during childhood, gene-regulation is expected to play an important role in its pathogenesis. This prompted us to explore beyond traditional gene finding approaches.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
J Med Internet Res
January 2025
Ophthalmology Department, First Affiliated Hospital of GuangXi Medical University, Nanning, China.
Background: In recent years, with the rapid development of machine learning (ML), it has gained widespread attention from researchers in clinical practice. ML models appear to demonstrate promising accuracy in the diagnosis of complex diseases, as well as in predicting disease progression and prognosis. Some studies have applied it to ophthalmology, primarily for the diagnosis of pathologic myopia and high myopia-associated glaucoma, as well as for predicting the progression of high myopia.
View Article and Find Full Text PDFAm J Ophthalmol
December 2024
Department of Ophthalmology, New Civil Hospital, Strasbourg University Hospital, FMTS, Strasbourg, France. Electronic address:
Purpose: To describe a new feature in pathologic myopia: perivascular patchy chorioretinal atrophy (PVCA) DESIGN: Cross-sectional study METHODS: 604 eyes of 312 highly myopic patients followed at Strasbourg University Hospitals were reviewed for the presence of PVCA lesions. Demographic, clinical, and paraclinical data (ultra-widefield retinography, optical coherence tomography (OCT), fluorescein and indocyanine green angiography images) were analyzed. Controls were matched for age, sex, and axial length (AL).
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Purpose: To investigate the 10-year changes in visual function and incidence of visual impairment (VI) in highly myopic eyes.
Methods: This longitudinal study enrolled highly myopic individuals who were followed up for 10 years. All participants underwent detailed ophthalmic examinations at baseline and follow-up visits.
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