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Self-Collected Testing for Sexually Transmitted Infections: A National Text Message Survey of Adolescents and Young Adults.

J Adolesc Health

January 2025

University of Michigan Department of Obstetrics and Gynecology, Ann Arbor, Michigan; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan; Department of Health Behavior and Health Equity, University of Michigan School of Public Health, Ann Arbor, Michigan. Electronic address:

Purpose: We aimed to analyze adolescent and young adults' (AYAs) perspectives on using sexually transmitted infection (STI) self-collection kits to help guide the provision and implementation of accessible and confidential reproductive health-care services for those who experience the burden of STIs and STI-related morbidity.

Methods: We utilized MyVoice, a nationwide text message survey of AYAs, to pose 6 open-ended questions on their perceptions and use of STI self-collection kits. Two independent reviewers used inductive content analysis to develop a codebook and analyze responses, and a third settled any coding discrepancies through discussion to reach consensus.

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An overview of sound source localization based condition monitoring robots.

ISA Trans

December 2024

Centre for Efficiency and Performance Engineering, University of Huddersfield, Huddersfield HD1 3DH, UK. Electronic address:

As artificial intelligence advances and demand for cost-effective equipment maintenance in various fields increases, it is worth insightful research on utilizing robots embedded with sound source localization (SSL) technology for condition monitoring. Combining the two techniques has significant advantages, which are conducive to further classifying and tracking abnormal sources, thereby enhancing system performance at a lower cost. The paper provides an overview of current acoustic-based robotic techniques for condition monitoring, highlights the common SSL methods, and finds that localization performance heavily depends on signal quality.

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Mechanisms for resistance to BCMA-targeted immunotherapies in multiple myeloma.

Blood Rev

January 2025

Department of Hematology, First Hospital of Jilin University, Changchun, Jilin, China. Electronic address:

Multiple myeloma (MM) remains incurable and patients eventually face the relapse/refractory dilemma. B cell maturation antigen (BCMA)-targeted immunotherapeutic approaches have shown great effectiveness in patients with relapsed/refractory MM, mainly including chimeric antigen receptor T cells (CAR-T), bispecific T cell engagers (TCEs), and antibody-drug conjugates (ADCs). However, their impact on long-term survival remains to be determined.

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Pathological diagnosis of central nervous system tumours in adults: what's new?

Pathology

December 2024

Department of Pathology, Amsterdam University Medical Centers/VUmc, Amsterdam, The Netherlands; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.

In the course of the last decade, the pathological diagnosis of many tumours of the central nervous system (CNS) has transitioned from a purely histological to a combined histological and molecular approach, resulting in a more precise 'histomolecular diagnosis'. Unfortunately, translation of this refinement in CNS tumour diagnostics into more effective treatment strategies is lagging behind. There is hope though that incorporating the assessment of predictive markers in the pathological evaluation of CNS tumours will help to improve this situation.

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Visceral fat distribution: Interracial studies.

Adv Clin Chem

January 2025

Department of Genetics, College of Basic Medical Sciences, Jilin University, Changchun, China. Electronic address:

Visceral adipose tissue, a type of abdominal adipose tissue, is highly involved in lipolysis. Because increased visceral adiposity is strongly associated with the metabolic complications related with obesity, such as type 2 diabetes and cardiovascular disease, there is a need for precise, targeted, personalized and site-specific measures clinically. Existing studies showed that ectopic fat accumulation may be characterized differently among different populations due to complex genetic architecture and non-genetic or epigenetic components, ie, Asians have more and Africans have less visceral fat vs Europeans.

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