Homosexual persons or human immunodeficiency virus (HIV)-infected patients frequently excrete cysts of nonpathogenic strains of Entamoeba histolytica ("Entamoeba dispar"). However, invasive amoebiasis is rare. We report two patients with AIDS and cytomegalovirus colitis in whom invasive amoebiasis was histologically diagnosed. It is concluded that E. histolytica has to be considered in HIV-infected patients with colitis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC229929PMC
http://dx.doi.org/10.1128/jcm.35.8.2168-2169.1997DOI Listing

Publication Analysis

Top Keywords

invasive amoebiasis
12
patients aids
8
aids cytomegalovirus
8
cytomegalovirus colitis
8
hiv-infected patients
8
patients
4
amoebiasis patients
4
colitis homosexual
4
homosexual persons
4
persons human
4

Similar Publications

Amoebas: the omnipotent organism and silent assassin.

Mol Biol Rep

January 2025

Exercise Applied Physiology Laboratory, Biomedical Department, Research Center in High Altitude Medicine and Physiology, Faculty of Health Sciences, University of Antofagasta, Antofagasta, Chile.

Amoebas are characterized by their unique ability to exist both as free-living organisms and, occasionally, as parasites within host tissues, earning them the designation 'amphizoic amoebae'. While amoebic infections are less prevalent, their health impact can be tremendous, leading to several diseases. In low-income countries, poor sanitation and socioeconomic conditions significantly increase the risk of amoebic infections, particularly E.

View Article and Find Full Text PDF

Adaptive approach to diagnosis of amebic liver abscess in non-endemic areas.

Diagn Microbiol Infect Dis

January 2025

Division of Infectious Diseases, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134, USA; Department of Medicine, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.

Entamoeba histolytica infections range from asymptomatic intestinal amebiasis to more severe syndromes like invasive colitis or hepatic abscess. While diagnostic tests available for assessing these infections have evolved, the optimal use of newer diagnostics like enteric multiplex Polymerase Chain Reaction (PCR) panels has not been fully established. Here we describe the case of a 34-year-old male with an amebic liver abscess (ALA) that was diagnosed via multiplex Gastrointestinal (GI) PCR panel on formed stool and subsequently confirmed by testing liver abscess fluid (off-label) on the same multiplex GI PCR panel leading to rapid diagnosis and targeted treatment modification with excellent outcome.

View Article and Find Full Text PDF

Amoebic liver abscess (ALA), a common tropical infection, is caused by (EH). For decades, the first-line treatment for ALA has been metronidazole which has several drawbacks. The thioredoxin reductase enzyme in EH is essential for its anti-oxidative defence and survival during tissue invasion.

View Article and Find Full Text PDF

-induced NETs are highly cytotoxic on hepatic and colonic cells due to serine proteases and myeloperoxidase activities.

Front Immunol

December 2024

Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, Mexico.

During intestinal and liver invasion by the protozoan parasite , extensive tissue destruction linked to large neutrophil infiltrates is observed. It has been proposed that microbicidal components of neutrophils are responsible for the damage, however, the mechanism by which they are released and act in the extracellular space remains unknown. In previous studies, we have shown that trophozoites induce NET formation, leading to the release of neutrophil granule content into extruded DNA.

View Article and Find Full Text PDF
Article Synopsis
  • - Ameboma is a rare complication from invasive amebiasis caused by a specific intestinal protozoan, leading to tumor-like inflammatory masses in the lower right abdomen.
  • - Symptoms can vary but often include intestinal obstruction and gastrointestinal bleeding, and while imaging techniques like CT and ultrasound can reveal colonic masses, biopsy remains the most reliable way to diagnose ameboma.
  • - Treatment generally involves targeting the protozoan causing the infection, with surgery being necessary for severe cases like intestinal obstruction or other serious complications.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!