Background: Hypertrophic pulmonary osteoarthropathy (HPOA) secondary to bronchogenic carcinoma can be associated with severe, disabling pain which is not always responsive to conventional treatment.

Aim: To report on the use of pamidronate to control resistant pain in HPOA in three cases.

Methods: A retrospective review of reported pain, chest X-ray and radionuclide bone scans was made.

Results: Pain relief was achieved in all three cases together with reduced radiolabel uptake in two cases.

Conclusions: Pamidronate appears to be an effective therapy for HPOA. Further investigation is warranted.

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http://dx.doi.org/10.1111/j.1445-5994.1997.tb01983.xDOI Listing

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