Hair cortical cell counting (HCCC) represents a non-invasive, in-vivo measure of cell kill in the human integument. Sixty-six patients undergoing conventionally fractionated, external beam radiotherapy for early stage carcinoma of the prostate had groin hair samples counted. This technique is a sensitive and reproducible measure of radiation effect and may have applicability as an in-vivo prediction tool or in the field of biological dosimetry. A repopulative follicular response occurring at 3-4 weeks may explain flattening of the dose response curve.
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http://dx.doi.org/10.1016/s0167-8140(97)00059-5 | DOI Listing |
BMJ Case Rep
January 2025
Endocrinology, Government Medical College Thiruvananthapuram, Thiruvananthapuram, Kerala, India.
We describe the case of a girl in her middle childhood who presented with signs of heterosexual precocious puberty in the form of axillary and pubic hair growth, acne and clitoromegaly. Investigations showed elevated androgens and autonomous cortisol excess, suggesting an adrenal source. CT imaging confirmed a left adrenal mass and multiple colonic polyps.
View Article and Find Full Text PDFAppl Microsc
December 2024
Department of Cosmetology, Hanseo University, Seosan, Chungnam, 31962, Republic of Korea.
This study investigates the impact of excessive bleaching on the external morphology and internal microstructure of hair, compared to untreated hair. Using scanning electron microscopy (SEM) and transmission electron microscopy (TEM), we observed significant changes in both the surface and internal structures of bleached hair. SEM analysis of normal hair revealed a relatively clean surface with intact cuticle scales, while bleached hair showed brittle, torn scales with a rough appearance.
View Article and Find Full Text PDFFront Vet Sci
December 2024
Faculty of Life and Environmental Sciences, Teikyo University of Science, Uenohara, Japan.
Despite the long history of the horse-human bond, our understanding of the brain and mind of horses remains limited due to the lack of methods to investigate their brain functions. This study introduces a novel methodology for completely non-invasive, multi-channel recording of electroencephalography (EEG) and evoked potentials in awake horses to examine equine auditory cortical processing. The new approach utilizes specially designed brush-shaped active electrodes that facilitate stable signal acquisition through the hair coat by penetrating electrode pins and integrated pre-amplifiers.
View Article and Find Full Text PDFArch Dermatol Res
December 2024
Department of Dermatology, Venereology and Leprology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India.
Introduction: Alopecia areata (AA) is a chronic, immune-mediated inflammatory disorder characterized by nonscarring hair loss. The management of AA poses challenges due to its unpredictable course and variable response to treatment. In this comparative study, we evaluated the efficacy and safety of oral apremilast, intralesional corticosteroids (ILC) and a combination of both in patients with patchy AA.
View Article and Find Full Text PDFAn Bras Dermatol
December 2024
Department of Internal Medicine, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Background: Alopecia areata is a highly frequent disease with great variability in clinical presentation, severity, and prognosis. It has a significant negative impact on quality of life, especially in the moderate and severe forms.
Objective: To disseminate guidelines, prepared by a group of Brazilian experts, for the treatment and follow-up of patients with alopecia areata.
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