Kayexalate (Roxane Labs, Columbus, OH) in sorbitol is commonly administered by the oral and rectal route for the treatment of hyperkalemia in patients with renal failure. It is believed to have minimal toxicity because it functions as a cation exchanger and is not absorbed. We herein report on a patient who developed identical serpiginous ulcers in the stomach and the terminal ileum after the use of Kayexalate. We believe that this drug could have significant gastrointestinal toxicity in specific patient groups and suggest tentative guidelines, both for the identification of such patients and for the safer use of Kayexalate in these circumstances.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0272-6386(97)90574-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recurrent gastrointestinal bleeding caused by cytomegalovirus duodenitis.
Rev Esp Enferm Dig
September 2024
Gastrenterology, Hospital Garcia de Orta, Portugal.
A 78-year-old male hospitalized due to acute pneumonia presented with hematemesis, melena and hypotension. Past medical history was relevant for prostate cancer with bone and lung metastasis under systemic chemotherapy. Upper gastrointestinal endoscopy revealed a 50mm serpiginous ulcer in the second portion of the duodenum with a visible vessel (Forrest IIa).
View Article and Find Full Text PDFDynamic Optical Coherence Tomography of Blood Vessels in Cutaneous Melanoma-Correlation with Histology, Immunohistochemistry and Dermoscopy.
Cancers (Basel)
August 2023
Department of Dermatology, University Hospital Augsburg, 86179 Augsburg, Germany.
Article Synopsis
- Dermoscopy enhances melanoma assessment, but histologic parameters and surgical intervention are essential for predicting tumor progression.
- This study evaluated blood vessel patterns in melanoma using dynamic optical coherence tomography (D-OCT) and correlated findings with dermoscopy and histology to assess malignancy risk.
- Results showed that atypical vessel shapes and increased density indicated higher tumor stages, while certain histologic markers correlated with D-OCT findings, suggesting D-OCT can noninvasively evaluate tumor vasculature prior to surgery.
Dynamic optical coherence tomography of chronic venous ulcers.
J Eur Acad Dermatol Venereol
January 2024
Department of Dermatology and Allergology, University Hospital Augsburg, Augsburg, Germany.
Background: Chronic ulcers, especially venous leg ulcers, are a major burden on the healthcare system. To date there are only few non-invasive established procedures for evaluation of blood perfusion in wounds. Dynamic optical coherence tomography (D-OCT) provides images of the skin's superficial vascularisation.
View Article and Find Full Text PDFVaricella Zoster Reactivation Manifesting as Serpiginous Peripheral Keratitis and Disciform Keratitis Occurring After Necrotizing Fasciitis in an Immunocompromised Male: A Case Report.
Cureus
June 2023
Plastic and Reconstructive Surgery, All India Institute of Medical Sciences, Rishikesh, IND.
Article Synopsis
- Reactivation of herpes zoster ophthalmicus (HZO) can occur without typical symptoms like neuralgia or a herpetic rash, often leading to corneal issues instead.
- A 45-year-old male, with a prior history of chickenpox and rheumatoid arthritis, experienced painful vision loss in one eye without any rash, later diagnosed with herpetic disciform keratitis.
- The patient's condition improved after treatment with acyclovir and steroids, and this case highlights a unique occurrence of HZO reactivation following necrotizing fasciitis, which hasn't been documented before.
Idiopathic recurrent pyoderma gangrenosum with cobalamin deficiency in a 62-year-old male: a case report.
Ann Med Surg (Lond)
March 2023
Department of Internal Medicine, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
Unlabelled: Pyoderma gangrenosum (PG) is a rare, neither infectious nor gangrenous, neutrophil-mediated inflammatory dermatosis. In 50-70% of cases, systemic disease is the underlying cause, and the remaining is idiopathic.
Case Presentation: The authors here present a case of a 62-year-old male with a history of recurrent ulcer over the dorsum of hand diagnosed with recurrent PG with cobalamin deficiency treated with intralesional steroid injection and topical antibiotics along with intramuscular vitamin B12 injections.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!