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Beneficial effects of the remifentanil/thiopental combination on cardiac function and redox status in diabetic rats.
Can J Physiol Pharmacol
November 2024
Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
This study aimed to examine the effect of thiopental monotherapy as well as its combination with different agents used in anesthesia induction, on cardiac function and redox state of rats with type 1 diabetes mellitus (T1DM). A total of 40 male rats were used in this study and randomly divided into five groups: thiopental (TIO), fentanyl + thiopental (FEN + TIO), remifentanil + thiopental (REM + TIO), midazolam + thiopental (MID + TIO), and dexmedetomidine + thiopental (DEX + TIO). Animals were anesthetized by intraperitoneal injection of thiopental 85 mg/kg, fentanyl 0.
View Article and Find Full Text PDFTechnical success and adverse event rates after endoscopic retrograde cholangiopancreatography using deep sedation with propofol.
Ann Gastroenterol
October 2024
Department of Gastroenterology and Hepatology (Janine B. Kastelijn, A. Merel van den Berg, Raju Talwar, Marije S. Koks, Karel J. van Erpecum, Paul Didden, Leon M.G. Moons, Frank P. Vleggaar).
Background: With the increasing complexity and prolonged duration of endoscopic retrograde cholangiopancreatography (ERCP) procedures, sedation shifted from conscious sedation with benzodiazepines to deep sedation with propofol. We assessed the technical success and adverse event rates of ERCP with deep versus conscious sedation.
Methods: Consecutive patients treated with ERCP in the University Medical Center Utrecht over a 7-year period (2010-2016) were screened for eligibility.
Comparative Efficacy and Safety of Anesthetic and Sedative Regimens for Endoscopic Retrograde Cholangiopancreatography: A Network Meta-Analysis.
Dig Dis
November 2024
Department of Anesthesiology, 904th Hospital of The Joint Logistics Support Force of the PLA, Wuxi, China.
Introduction: This study evaluates the efficacy and safety of various anesthetic and sedative regimens for endoscopic retrograde cholangiopancreatography (ERCP) procedures.
Methods: A systematic search was conducted across PubMed, Web of Science, Scopus, and Embase to identify randomized controlled trials (RCTs) published until March 2024. Primary outcomes included procedure time, patient satisfaction, oxygen saturation (SpO2), incidence of SpO2 below 90%, and adverse events.
Capturing the incidence of patient agitation amongst conscious sedation ERCPs and the impact on therapeutic outcomes.
Eur J Gastroenterol Hepatol
October 2024
Department of Gastroenterology, Mater Misericordiae University Hospital.
Background: Completing advanced endoscopic procedures such as endoscopic retrograde cholangiopancreatography (ERCP) under conscious sedation is challenging. International recommendations favor enhanced sedation (e.g.
View Article and Find Full Text PDFSedation reversal trends at outpatient ambulatory endoscopic center in-hospital ambulatory procedure center using a triage protocol.
World J Gastrointest Endosc
July 2024
Division of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin Hospitals and Clinics, Madison, WI 53705, United States.
Article Synopsis
- - The study investigates the rates of sedation reversal during outpatient endoscopy in different settings, focusing on how a triage tool helps direct higher-risk patients to an in-hospital center for better outcomes.
- - Data from over 97,000 procedures at an ambulatory endoscopy center (AEC-DHC) and nearly 23,000 at an in-hospital ambulatory procedure center (APC) were analyzed from April 2013 to September 2019, revealing low rates of sedation reversal (0.017% at AEC-DHC and 0.04% at APC).
- - The study found that patients needing sedation reversal at both centers had varying characteristics, with significant differences in factors like age, ASA classification,
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