[Negative relationship between variation of nuclear and mitochondrial genomes in populations of Arctic Mongoloids of Northeastern Asia].

Incompatibility of variation of nuclear and mitochondrial genomes was shown in four Arctic Mongoloid populations. An increase in heterozygosity was accompanied by a decrease in variation of mtDNA in the Koryaks-Chukchi-Asian Eskimo population series, and corresponds to the gradient of severity of the environment. An explanation is proposed based on the assumption of the key role of selective processes in the formation of the genetic (nuclear and mitochondrial) structure of Arctic Mongoloid populations in connection with long-term adaptation to extreme environment.