In all countries from which reliable statistics are available, there has been a striking increase in lung cancer mortality in recent decades. At present lung tumours are the most frequent organ cancer in men. Epidemiological, clinical and laboratory studies have clearly shown that the inhalation of cigarette smoke is a major risk factor in lung cancer.
Download full-text PDF |
Source |
---|
JAMA Netw Open
March 2025
SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, Washington.
Importance: Contact days-days with health care contact outside the home-are a measure of how much of a patient's life is consumed by health care. Clinical trials, with a more uniform patient mix and protocolized care, provide a unique opportunity to assess whether burdens differ by individuals' sociodemographic backgrounds.
Objective: To characterize patterns of contact days for older adults with cancer participating in clinical trials.
JAMA Oncol
March 2025
The Program on Regulation, Therapeutics, and Law, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Chemistry
March 2025
İstanbul Üniversitesi-Cerrahpaşa: Istanbul Universitesi-Cerrahpasa, Institute of nanotechnology and biotechnology, alkent 2000 mah. yiğittürk cad. no 5, 35100, İSTANBUL, TURKEY.
Cancer remains a critical global health challenge, necessitating advanced drug delivery systems through innovations in materials science and nanotechnology. This study evaluates Gadolinium Metal-Organic Frameworks (Gd-MOFs) as potential drug delivery systems for anticancer therapy, particularly when combined with radiotherapy. Gd-MOFs were synthesized using terephthalic acid and gadolinium (III) chloride hexahydrate, then loaded with methotrexate (MTX).
View Article and Find Full Text PDFCancer Epidemiol Biomarkers Prev
March 2025
National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, Chungcheongbuk-do, Korea (South), Republic of.
Background: Telomere length shortens with age and is associated with an increased risk of numerous chronic diseases. However, the causal direction between telomere length and cancer risk remains uncertain. This study aimed to assess the causal impact of telomere length on cancer risk using Mendelian randomization(MR) analysis.
View Article and Find Full Text PDFOncologist
March 2025
Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Background: Previous research demonstrates longer survival for patients with lung-only metastatic pancreatic adenocarcinoma (mPDAC) compared to liver-only mPDAC. The objective of this study is to understand the survival differences, impact of chemotherapy, and associated genomic features of mPDAC that is isolated to either the liver or lung.
Patients And Methods: Longitudinal clinical outcomes and molecular sequencing data were retrospectively analyzed across 831 patients with PDAC across all stages whose tumors first metastasized to the liver or lung.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!