The contamination of birds with pathogenic staphylococci was followed up during their slaughter handling and trimming at two poultry-dressing houses. It was found that water cooling and evisceration were mostly contributing to contamination. Taking part in the dissemination of Staphylococcus infection were also the female workers on the slaughter belt, especially those that had wounds on their hands. Studied were the properties of a total of 881 strains of staphylococci, 43.35 per cent of them being defined as Staph. aureus, and 56.64 per cent--as Staph. edidermidis.
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Vet World
November 2024
Laboratory of Avian Diseases, School of Veterinary Medicine and Animal Science, Department of Pathology, University of São Paulo, São Paulo, Brazil.
Background And Aim: Fowl adenovirus (FAdV) is the etiological agent of inclusion body hepatitis (IBH) and hepatitis-hydropericardium syndrome (HHS) in poultry. It is also detected in chickens with runting and stunting syndrome (RSS). FAdV has been detected worldwide, and genotypes 8a, 8b, and 11 have been identified in chickens with enteric problems in Brazil.
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January 2025
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.
Recombinant adeno-associated viruses (rAAVs) have emerged as promising vaccine vectors due to their enduring efficacy with a single dose. However, insufficient cellular immune responses and the random and non-specific distribution of AAVs post-injection may hinder the development of AAV vaccines. Here, a novel Pickering emulsion platform stabilized by biomineralized manganese nanoparticles and aluminum hydroxide, which can rapidly and efficiently load AAVs, is reported.
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January 2025
Department of Food Science and Technology, College of Agriculture, Isfahan University of Technology, Isfahan, 84156-83111, Iran; Research Institute for Biotechnology and Bioengineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran.
Infectious hematopoietic necrosis virus (IHNV) is a serious pathogen in the salmonid aquaculture industry and leads to economic losses in the world. This study aimed to develop a new oral DNA vaccine designed to protect rainbow trout against infection by IHNV. Fish were administered via the oral route by the attenuated Salmonella enterica serovar Typhimurium as a carrier of pcDNA3.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Bio-Microfluidics Lab, Department of Electrical Engineering and Information Technology, Iranian Research Organization for Science and Technology, Tehran, Iran.
Water pollution, driven by a variety of enduring contaminants, poses considerable threats to ecosystems, human health, and biodiversity, highlighting the urgent need for innovative and sustainable treatment approaches. Ozone-based advanced oxidation processes (AOPs) have demonstrated significant efficacy in breaking down stubborn pollutants, such as organic micropollutants and pathogens, that are not easily addressed by traditional treatment techniques. This review offers an in-depth analysis of ozonation mechanisms, covering both the direct oxidation by ozone and the indirect reactions facilitated by hydroxyl radicals, emphasizing their effectiveness and adaptability across various wastewater matrices.
View Article and Find Full Text PDFVirulence
December 2025
Manchester Fungal Infection Group (MFIG), Division of Evolution, Infection, and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Sulfur metabolism is an essential aspect of fungal physiology and pathogenicity. Fungal sulfur metabolism comprises anabolic and catabolic routes that are not well conserved in mammals, therefore is considered a promising source of prospective novel antifungal targets. To gain insight into sulfur-related metabolism during infection, we used a NanoString custom nCounter-TagSet and compared the expression of 68 key metabolic genes in different murine models of invasive pulmonary aspergillosis, at 3 time-points, and under a variety of conditions.
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