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Mendelian randomization study investigating the relationship between nutrients and polycystic ovary syndrome.
Int J Gynaecol Obstet
November 2024
Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Objective: Polycystic ovary syndrome (PCOS) affects many women and is linked to nutrient intake, but the causal role of nutrients is unclear. Our study used Mendelian randomization (MR) to explore this relationship.
Methods: We employed two-sample MR to investigate the causal effects of four macronutrients (carbohydrates, fats, sugars, proteins) and 12 micronutrients (vitamin A [retinol], folate, vitamin B6, vitamin B12, vitamin C [ascorbic acid], vitamin D, vitamin E [alpha-tocopherol], magnesium, calcium, iron, selenium, and zinc) on the risk of PCOS based on their circulating levels.
Overweight Leads to an Increase in Vitamin E Absorption and Status in Mice.
Mol Nutr Food Res
December 2024
Aix-Marseille Université, INRAE, INSERM, C2VN, Marseille, France.
Article Synopsis
- This study looks into why obese individuals may have low vitamin E (VE) levels, specifically whether it's due to issues with how VE is absorbed in the intestines.
- After 12 weeks of a high-fat diet, mice showed increased weight and fat levels compared to those on a control diet, but surprisingly, they had higher levels of α-tocopherol (a form of vitamin E) in their blood and liver.
- The results suggest that even with obesity, these mice actually absorb vitamin E more effectively rather than having impaired absorption.
Pasta Incorporating Olive Pomace: Impact on Nutritional Composition and Consumer Acceptance of a Prototype.
Foods
September 2024
LAQV/REQUIMTE, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Street of Jorge Viterbo Ferreira, 4050-313 Porto, Portugal.
The food industry is encouraged to develop new sustainable foodstuffs, and agri-food by-products can serve as valuable ingredients in these formulations. In this work, olive pomace (OP), a by-product of olive oil production, was incorporated as an ingredient in pasta. The changes in the nutritional composition and consumer acceptance were assessed, aiming to scale up the production.
View Article and Find Full Text PDFAssociation of prenatal vitamin E levels with child asthma and wheeze.
Pediatr Allergy Immunol
August 2024
Department of Pediatrics and Environmental Medicine & Climate Science, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: We investigated the individual and interaction effects of maternal plasma 𝛂- and ϒ-tocopherol levels (vitamin E isomers) on child asthma and wheeze at age 8-9.
Methods: Mother-child dyads were enrolled between 2006 and 2011 into the Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE) prenatal cohort. Maternal second-trimester samples were analyzed for tocopherol and lipid concentrations.
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