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Self-supervised denoising of grating-based phase-contrast computed tomography.
Sci Rep
December 2024
Research Group Biomedical Imaging Physics, Department of Physics, TUM School of Natural Sciences, Technical University of Munich, 85748, Garching, Germany.
In the last decade, grating-based phase-contrast computed tomography (gbPC-CT) has received growing interest. It provides additional information about the refractive index decrement in the sample. This signal shows an increased soft-tissue contrast.
View Article and Find Full Text PDF[Evaluating patient experience in oncology and chronic diseases: Critical analysis of available tools (PROMs, PREMs, Satisfaction)].
Bull Cancer
December 2024
IRMAIC, université Reims Champagne Ardenne, 51, rue Cognacq-Jay, 51100 Reims, France; Département d'oncologie médicale, Institut Godinot, 1, rue du Général-Koenig, 51100 Reims, France.
Care quality assessment emerged in the late 1990s, leading to the integration of users into healthcare systems. To integrate patient perceptions, resources such as PROs (Patient Reported Outcomes), PROMs (Patient-Reported Outcome Measures), satisfaction and patient experts or partners have been developed. PREMs (Patient-Reported Experience Measures) have recently emerged, bringing a fresh perspective to improving quality and care pathways, but are still little-known.
View Article and Find Full Text PDFPhenotypic variability in a family with an inherited KAT6A frameshift variant.
Eur J Med Genet
December 2024
Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark; Centre for Rare Diseases, Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Denmark.
KAT6A syndrome or Arboleda-Tham Syndrome (ARTHS; OMIM #616268) is a syndromic neurodevelopmental disorder mainly presenting with variable degrees of intellectual disability (ID) and developmental delay (DD), especially speech delay, hypotonia and autism spectrum disorders/behavioral problems. Multiple organ-systems including eyes, heart, gastrointestinal and neurological system can be involved. Other phenotypic features with a suggested association to KAT6A include immune dysfunction and pituitary anomalies.
View Article and Find Full Text PDFPopulation Proteomics: A Tool to Gain Insights Into the Inflamed Periodontium.
Proteomics
December 2024
Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany.
Periodontitis, characterized by inflammatory loss of tooth-supporting tissues associated with biofilm, is among the most prevalent chronic diseases globally, affecting approximately 50% of the adult population to a moderate extent and cases of severe periodontitis surpassing the one billion mark. Proteomics analyses of blood, serum, and oral fluids have provided valuable insights into the complex processes occurring in the inflamed periodontium. However, until now, proteome analyses have been primarily limited to small groups of diseased versus healthy individuals.
View Article and Find Full Text PDFA rapid systematic review of the effect of health or peer volunteers for diabetes self-management: Synthesizing evidence to guide social prescribing.
PLOS Glob Public Health
December 2024
Department of Family Practice, The University of British Columbia, Vancouver, Canada.
Social prescribing is a model of care, usually in the community-setting, which aims to address people's unmet social needs. Volunteers support primary health care and community-based care in non-medical roles. However, few studies focus on volunteers in social prescribing, therefore, aimed to synthesize the effect of health or peer volunteer-led interventions on psychosocial and behavioural outcomes for middle-aged and older adults with Type 2 Diabetes Mellitus (T2DM) to inform future work for volunteering in social prescribing.
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