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Cochlear Implant Electrode Placement and Music Perception.

JAMA Otolaryngol Head Neck Surg

January 2025

Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.

Importance: Cochlear implants enable improvements in speech perception, but music perception outcomes remain variable. Image-guided cochlear implant programming has emerged as a potential programming strategy for increasing the quality of spectral information delivered through the cochlear implant to improve outcomes.

Objectives: To perform 2 experiments, the first of which modeled the variance in music perception scores as a function of electrode positioning factors, and the second of which evaluated image-guided cochlear implant programming as a strategy to improve music perception with a cochlear implant.

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When rendering the visual scene for near-eye head-mounted displays, accurate knowledge of the geometry of the displays, scene objects, and eyes is required for the correct generation of the binocular images. Despite possible design and calibration efforts, these quantities are subject to positional and measurement errors, resulting in some misalignment of the images projected to each eye. Previous research investigated the effects in virtual reality (VR) setups that triggered such symptoms as eye strain and nausea.

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Background: Alzheimer's Disease (AD) is associated with sleep disturbances. Moreover, individuals with sleep disturbances have been reported to have a higher risk for developing AD. The measurement of sleep behavior therefore opens the opportunity for a potential digital biomarker of AD.

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Background: Sleep disorders as a contributing factor to cognitive impairment have spurred growing interest. The advent of digital technology facilitates the collection of comprehensive sleep measures in a home setting. The objective of this study is to examine the association between digital sleep measures and the Montreal Cognitive Assessment (MoCA).

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Background: The present study examined OSA using an objective home sleep test in 81 adults with DS (aged 25 ∼ 61 years) and evaluated associations between sleep-disordered breathing problems and biomarkers of AD pathology (PET Aβ and tau) and symptomology (cognitive performance and depressed mood).

Method: As part of the ABC-DS study, participants completed a 2.5-hour battery of cognitive measures and underwent MRI and PET imaging scans and a blood draw.

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