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Endometrial scratching in unexplained repeated implantation failure causes two competing forces, angiogenesis and anti-angiogenesis: An RCT study.
Int J Reprod Biomed
April 2024
Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Background: A significant association between endometrial vascularity and pregnancy has been shown in previous research, while poor vascularization was attributed to repeated implantation failure (RIF). One possible approach to enhance angiogenesis for successful implantation is endometrial scratching (ES).
Objective: The purpose was to investigate endometrial responses to scratching by profiling angiogenesis-related gene expression in unexplained RIF participants.
Multicenter Clinical Trials Analyzing Efficacy and Safety of Topical Cortex Phellodendri Compound Fluid in Treatment of Diabetic Foot Ulcers.
Med Sci Monit
August 2020
Department of Peripheral Vascular Surgery, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China (mainland).
Article Synopsis
- The study aimed to evaluate the effectiveness of cortex phellodendri compound fluid (CPCF) in treating diabetic foot ulcers (DFU) compared to the Kangfuxin solution (KFS).
- Conducted over four years, 720 patients were divided into an experimental group (CPCF) and a control group (KFS), with assessments of ulcer size, growth factor levels, treatment effectiveness, and adverse events after four weeks.
- Results showed CPCF significantly improved ulcer healing and growth factor levels without increasing adverse event rates, indicating it is a safe and effective treatment option for DFU.
Decreased growth rate of lung metastatic lesions after splenectomy in mice.
Eur Surg Res
December 2006
Department of Surgery 1, Oita University Faculty of Medicine, Yufu, Oita, Japan.
Background: The effect of splenectomy on hematogenous metastases of malignant tumors remains controversial. The aim of this study was to clarify the effect of splenectomy on hematogenous metastases in an animal model.
Methods: Colon 26 cancer cells were inoculated into the lateral tail vein of 90 mice.
Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia.
Leukemia
March 2005
Servicio de Hematología, Hospital Universitario de Salamanca and Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Spain.
Bone marrow samples from 43 adult patients with de novo diagnosed acute myeloid leukemia (AML)--10 acute promyelocytic leukemias (APL) with t(15;17), four AML with inv(16), seven monocytic leukemias and 22 nonmonocytic leukemias--were analyzed using high-density oligonucleotide microarrays. Hierarchical clustering analysis segregated APL, AML with inv(16), monocytic leukemias and the remaining AML into separate groups. A set of only 21 genes was able to assign AML to one of these three classes: APL, inv(16) and other AML subtype without a specific translocation.
View Article and Find Full Text PDFAssignment of FGF13 to human chromosome band Xq21 by in situ hybridization.
Cytogenet Cell Genet
July 1997
INSERM Unité 119, Marseille, France.
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