Hypervascularity in Lhermitte-Duclos disease--case report.

Neurol Med Chir (Tokyo)

Department of Neurosurgery, Asahikawa Medical College, Hokkaido.

Published: May 1997

AI Article Synopsis

  • - A 61-year-old man was diagnosed with Lhermitte-Duclos disease, characterized by a hypervascular dysplastic gangliocytoma, which led to gait issues.
  • - Imaging studies (CT and MRI) revealed tumor enhancement after contrast injection, and angiography indicated a tumor stain.
  • - Histology showed a double-layered structure with myelinated axons, dysplastic granular cells, and many thin-walled blood vessels; partial tumor resection improved the patient's neurological symptoms.

Article Abstract

A 61-year-old male presented with a hypervascular variant of dysplastic gangliocytoma (Lhermitte-Duclos disease) manifesting as gait disorder. Computed tomography and magnetic resonance imaging both showed enhancement of the tumor after injection of contrast medium. Angiography demonstrated a tumor stain. Histological examination showed a double-layered structure comprising an outer layer of myelinated axons and an inner layer of dysplastic granular cells, and numerous dilated thin-walled blood vessels. Partial resection of the tumor resulted in resolution of the neurological deficit.

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Source
http://dx.doi.org/10.2176/nmc.37.403DOI Listing

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