On account of the reported better results of open surgical dismembered pyeloplasty over the new techniques of endopyelotomy (95-100% versus 70-80%), the Author takes into consideration the factors which might contribute to this difference in results. Among these factors, the etiology of the obstruction seems to be of importance. In fact, while dismembered pyeloplasty involve the complete removal of both the anatomical and functional causes of obstruction (stenosis, adynamic junction), endopyelotomy should only overcome the anatomic causes of obstruction, most likely being inadequate in the functional causes of obstruction due to aperistalism of the junction. Another factor involved in the lower success rate of endopyelotomy is the absence of ampullar resection which may interfere with the recovery of a normal peristalsis. A careful and updated evaluation of the etiology and pathophysiology of pyeloureteral junction is therefore mandatory for a meaningful choice of the appropriate management and for the screening of patients who will benefit the most from each type of treatment.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Horseshoe kidney presenting with features of left ureteropelvic junction obstruction-insights into management: a case report and review of the literature.
J Med Case Rep
January 2025
Department of Surgery, School of Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Background: Horseshoe kidney is the most common renal fusion anomaly, occurring in approximately 1 in 500 individuals worldwide. It is characterized by abnormalities in kidney position, rotation, and vascular supply. While often asymptomatic, horseshoe kidneys can lead to urological complications, primarily due to ureteric obstruction and impaired urinary drainage.
View Article and Find Full Text PDFDoes thiol-disulphide balance in tissue and serum play a role in disease management in ureteropelvic junction stenosis?
J Pediatr Urol
November 2024
Department of Urology, Ankara City Hospital, Ankara, Türkiye. Electronic address:
Background: The study aimed at evaluating the role of thiol-disulphide balance parameters [native thiol (SH), total thiol (SH + SS), disulphide (SS), disulphide/native thiol ratio (% SS/SH), disulphide/total thiol ratio (% SS/Total Thiol) and native thiol/total thiol ratio (%SH/Total Thiol)], which are important oxidative stress markers in the congenital ureteropelvic junction (UPJ) stenosis, in the diagnosis of the disease, and its role in determining the need for surgery and follow-up.
Materials And Methods: This prospective study included 30 children diagnosed with congenital intrinsic ureteropelvic junction obstruction (UPJO) and a control group of 30 healthy children admitted to the pediatric clinic between January 2016 and February 2017. The children with UPJO underwent laparoscopic dismembered pyeloplasty.
Modified robot-assisted laparoscopic dismembered pyeloplasty for adult patients with horseshoe kidney: techniques and medium-term outcomes.
Minerva Urol Nephrol
November 2024
Department of Urology, Peking University First Hospital, Beijing, China -
Background: The aim of this study was to report our technique and medium-term outcomes of modified robot-assisted laparoscopic dismembered pyeloplasty (RALDP) in the Lithotomy Trendelenburg position for treating adult ureteropelvic junction obstruction (UPJO) with horseshoe kidney (HSK).
Methods: Between March 2021 and March 2023, 11 adult patients with UPJO and HSK underwent modified RALDP in the lithotomy Trendelenburg position. Patient demographic characteristics, perioperative parameters, and follow-up outcomes were collected prospectively and analyzed.
Expression of tissue fibrosis genes in congenitally obstructed pyeloureteral junction and biomarkers of renal damage.
Cent European J Urol
February 2024
Clinic of Gastroenterology, Nephrourology and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Article Synopsis
- The study aimed to explore how fibrosis-related genes in obstructed ureteral tissue relate to renal damage markers and preoperative renal scans.
- Researchers collected urine and blood samples pre-surgery, analyzing various biomarkers and gene expressions from obstructed tissue samples.
- The results showed certain negative correlations between urinary albumin and expressions of TGFβ1 and VEGFA in the obstructive tissue, but overall, no direct links were found between gene expressions and renal damage biomarkers.
Unique Variants of Megacalycosis on Magnetic Resonance Urography.
Urology
December 2024
Department of Pediatric Urology, Emory University and Children's Healthcare of Atlanta, Atlanta, GA.
Objective: To present a unique set of patients diagnosed with megacalycosis by magnetic resonance urography (MRU) to re-evaluate the definition of megacalycosis and provide a new perspective on diagnosis and treatment.
Materials And Methods: A retrospective chart review of patients with megacalycosis as diagnosed by MRU was conducted. MRU was performed to determine the presence of obstruction, further visualize renal anatomy, and clarify the presence of megacalycosis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!