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Porcine Lymphotropic Herpesviruses (PLHVs) and Xenotranplantation.
Viruses
June 2021
Institute of Virology, Free University, 14163 Berlin, Germany.
Porcine lymphotropic herpesviruses -1, -2 and -3 (PLHV-1, PLHV-2 and PLHV-3) are gammaherpesviruses which are widespread in pigs. They are closely related to the Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus, both of which cause severe diseases in humans. PLHVs are also related to bovine and ovine gammaherpesviruses, which are apathogenic in the natural host, but cause severe diseases after transmission into other species.
View Article and Find Full Text PDFPrimary effusion lymphoma occurring in the setting of transplanted patients: a systematic review of a rare, life-threatening post-transplantation occurrence.
BMC Cancer
April 2021
Pathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100, Terni, Italy.
Background: Primary effusion lymphoma is a rare, aggressive large B-cell lymphoma strictly linked to infection by Human Herpes virus 8/Kaposi sarcoma-associated herpes virus. In its classic form, it is characterized by body cavities neoplastic effusions without detectable tumor masses. It often occurs in immunocompromised patients, such as HIV-positive individuals.
View Article and Find Full Text PDFIatrogenic solid tumors following immunosuppressive therapy.
Semin Diagn Pathol
July 2018
Department of Pathology, Presbyterian Shadyside Hospitals, University of Pittsburgh Medical Center, 5230 Centre Avenue Pittsburgh, PA 15232, United States. Electronic address:
Immunosuppression induced by chronic medication, such as occurs post-transplantation, may increase a patient's risk of developing solid tumors. These are often rare tumors characterized by odd presentations. This review focuses on commonly encountered iatrogenic, non-hematopoietic solid tumors following immunotherapy and provides a practical approach to their diagnosis.
View Article and Find Full Text PDFIn kidney transplant patients, skin cancer is the most commonly involved neoplasm. More than 90% of post-transplantation skin cancers are nonmelanoma skin cancers (NMSCs). The majority of them are squamous cell carcinomas and basal cell carcinomas.
View Article and Find Full Text PDFOutcome of second kidney transplantation in patients with previous post-transplantation Kaposi's sarcoma: A French retrospective study.
Clin Transplant
November 2017
Department of Dermatology and Allergology, University Paris VI, Hôpital Tenon, Paris, France.
This retrospective study concerned 8 patients with post-transplantation Kaposi's sarcoma (pt-KS) after a first kidney transplant who later had a second kidney transplantation. Pt-KS was widespread, with lymph node or visceral involvement in 7 cases. Complete remission was observed in 6 cases and partial remission in 2.
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