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Vacuum-Assisted Eggshell-Type Bone Debridement with Implantation of Antibiotic-Impregnated Bone Substitute for Treatment of Calcaneal Osteomyelitis with Subsequent Charcot's Reconstruction: A Case Report.
J Am Podiatr Med Assoc
September 2024
‡Department of Medicine, Yale University School of Medicine, New Haven, CT.
Charcot's neuroarthropathy complicated by calcaneal osteomyelitis can be difficult to treat. Various surgical techniques describe how to manage these conditions. Eggshell-type debridement with application of antibiotic-impregnated bone substitute is a viable option that eliminates infected bone and allows staged reconstructive surgery.
View Article and Find Full Text PDFNaringin exerts antibacterial and anti-inflammatory effects on mice with Staphylococcus aureus-induced osteomyelitis.
J Biochem Mol Toxicol
July 2024
Department of Orthopedics, Xiangyang Central HospitaI, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China.
Osteomyelitis is an invasive bone infection that can lead to severe pain and even disability, posing a challenge for orthopedic surgery. Naringin can reduce bone-related inflammatory conditions. This study aimed to elucidate the function and mechanism of naringin in a Staphylococcus aureus-induced mouse model of osteomyelitis.
View Article and Find Full Text PDFNASCI case of the month: extensive ascending aortic graft infection with underlying chronic sternal osteomyelitis-a rare and high-risk complication.
Int J Cardiovasc Imaging
July 2024
Division of Cardiovascular Imaging, Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Thoracic aortic graft infections are infrequent yet grave complications of cardiovascular surgery. Risk factors include prolonged operative time, postoperative wound infections, and patient-specific risk factors like diabetes or malnutrition (Van Hemelrijck et al., Vessel Plus 6:47, 2022).
View Article and Find Full Text PDFOsteomyelitis and non-coding RNAS: A new dimension in disease understanding.
Pathol Res Pract
March 2024
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Osteomyelitis, a debilitating bone infection, presents considerable clinical challenges due to its intricate etiology and limited treatment options. Despite strides in surgical and chemotherapeutic interventions, the treatment landscape for osteomyelitis remains unsatisfactory. Recent attention has focused on the role of non-coding RNAs (ncRNAs) in the pathogenesis and progression of osteomyelitis.
View Article and Find Full Text PDFOur Experiences in the Treatment of Anterior Chest Wall Infections (2015 - 2021).
Mater Sociomed
June 2022
Clinic for Cardiovascular Surgery, Clinical Center University of Sarajevo, Bosnia and Herzegovina.
Background: Sternotomy is a classical surgical procedure for approaching the heart and mediastinum. Sternotomy wound infections can be superficial or deep.
Objective: The aim of this study is to retrospectively evaluate the results of two treatments for deep sternal wound infection (DSWI), closed treatment (debridement, refixation and retrosternal irrigation) and open treatment (debridement, VAC therapy and then pectoral flap).
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