5 patients with multiple left heart myxomas have been followed for 30 years. There were 4 females and 1 male at the age of 20-50 years. Two-dimensional echocardiography was used for the proper diagnosis in all cases. Open-heart surgery is the only possible method of treatment in such a situation. All the patients have been successfully operated on. To prevent the recurrence the resection of myxomas with a part of interatrial septum and endocardium was performed. The trans-sternal approach is the optimal one for the surgery of myxomas.
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