Distribution of gene markers of blood groups (ABO, RH, MN, KEL, and FY), erythrocyte enzymes (SOD-A and 6-PGD) and serum proteins (Hp, Gc, Tf, and ChE2) was studied in 10 ethnographic and geographic groups of Komis. Some of the groups studied differ significantly in the allele frequencies--B-ABO (0.163-0.289), Fy alpha (0.496-0.693), K (0.018-0.076)--and in haplotype frequencies of RH system--CDe (0.237-0.403), cDE (0.219-0.351), and cde (0.225-0.425). Average gene frequencies in Komis are considered in regard to ethnogenesis of the nation. It is demonstrated that Komis are genetically close to Finno-Ugrian ethnic groups of the Ural territory, but are different from Baltic Finns.

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