Thorough clinical, allergologic and immunologic examination of 65 patients who worked as building painters in contact with organic solvents proved these agents, not being allergens, to contribute in formation of occupational bronchial asthma. This type of bronchial asthma is characterized by some clinical features and pathogenetic mechanisms. A complex of clinical, allergologic and immunologic methods was elaborated to diagnose this type of bronchial asthma.

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