The Nd-YAG laser is widely used in endoscopy. Laser therapy either by contact or non-contact method, can be considered the best palliative option for patients affected by airway obstruction due to endoluminal malignant tumours. It aims at the improvement of breathing conditions and symptomatology. In patients affected by benign obstructions, it often allows to obtain curative results avoiding the use of traditional surgery. From 1988 to 1993 at the First Department of Surgery of the University of Rome "La Sapienza", 163 treatments out of 111 clinical cases affected by airway obstruction, caused by malignant tumours considered inoperable or relapsed after operation, or by vegetating benign tumours, or granulomas or fibrous diaphragms were performed. The symptomatological improvement and beneficial changes in functional breathing tests, haemogasanalysis, and X-ray findings were registered 24-48 hours after each treatment. The results showed an improvement in functional breathing values especially after treatment of the main airways such as trachea and main bronchi. The therapy offered an acceptable quality of life. A fairly good number of patients may also return to radio and chemotherapy, if previously interrupted.
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Respir Res
January 2025
Microbial Antibodies and Technologies, Research and Early Development, Vaccines and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by airway obstruction and inflammation. Non-typeable Haemophilus influenzae (NTHi) lung infections are common in COPD, promoting frequent exacerbations and accelerated lung function decline. The relationship with immune responses and NTHi are poorly understood.
View Article and Find Full Text PDFBMC Anesthesiol
January 2025
Department of Anesthesiology, Peking Union Medical College Hospital, Beijing, China.
Background: Halo-pelvic traction is a relatively safe treatment for preoperative spinal deformity correction in patients with severe scoliosis. Common device-related complications include local infection, back discomfort, and nerve compression symptoms. However, there are potential risks of mechanical compression of bronchial structures, especially in patients with severe thoracic lordosis and scoliosis, which can lead to life-threatening airway obstruction.
View Article and Find Full Text PDFInt Emerg Nurs
January 2025
Department of Pharmacy, Health and Nutritional Sciences (DFSSN) University of Calabria, Rende, CS Italy.
Objective: The objective of this systematic review is to comprehensively evaluate the effectiveness and safety of negative pressure, anti-choking devices (ACDs) in managing severe foreign body airway obstructions (FBAO) compared to traditional techniques such as the Heimlich maneuver.
Methods: A comprehensive literature search was conducted in major databases to identify studies published within the past five years. Eligible studies were appraised for quality using the Critical Appraisal and Data Extraction Tool.
Turk J Emerg Med
January 2025
Department of Emergency and Trauma, Hospital Sultan Haji Ahmad Shah, Pahang, Malaysia.
Snake-related injury (SRI) is one of the most common medical emergencies encountered in tropical countries such as Malaysia. The majority of snake bites are nonvenomous, while the less common venomous snakebite can cause major disability or even death. There are 16 pit viper species documented in Malaysia which can be categorized based on their habitat.
View Article and Find Full Text PDFIndian J Crit Care Med
November 2024
Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Objective: To study the efficacy of intravenous dexamethasone in preventing postextubation airway obstruction (PEAO).
Design: A double-blinded randomized controlled trial.
Study Setting: The study was conducted in level 3 PICU at AIIMS, Raipur, India, from December 2019 to September 2022.
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