Objectives: To review the literature and evaluate the evidence for the diagnostic outcome of arthrography, computed tomography (CT) and magnetic resonance imaging (MRI) in the assessment of temporomandibular joint (TMJ) disc position.
Methods: A literature search from 1978 to 1994 was conducted. Data on sensitivity, specificity, predictive values and likelihood ratios were collected and, if not available, calculated for each imaging method. Measures of observer performance were also recorded.
Results: In total, more than 400 publications were retrieved on imaging of TMJ disc position, 219 on arthrography, 99 on CT and 147 on MRI, with a marked decrease in recent years. The majority of the publications (54%) presented series of patients. The diagnostic outcome cold be obtained from only 7% of the studies and the observer performance from only two of these. Arthrography had the highest diagnostic outcome for the diagnosis of anterior disc position; sensitivity 0.90, specificity 0.80, positive predictive value 0.88 and negative predictive value 0.82. Corresponding figures for CT were 0.66, 0.68, 0.66 and 0.74 and for MRI 0.86, 0.63, 0.67 and 0.83. The diagnostic outcomes expressed as the likelihood ratios for positive test outcome were 4.5 for arthrography, 2.3 for MRI and 2.1 for CT. The outcomes in diagnosing sideways and rotational displacements were higher for MRI (sensitivity 0.81, specificity 0.87, positive predictive value 0.82, negative predictive value 0.88) than for arthrography (0.64, 0.83, 0.70, 0.79). The likelihood ratios were 6.2 for MRI and 3.8 for arthrography. The interobserver performance ranged between moderate to substantial for arthrography and was almost perfect for MRI.
Conclusions: Based on current evidence on the diagnostic outcome, MRI seems to be the method of choice for diagnosing TMJ disc position. Arthrography has a higher diagnostic outcome for anterior disc position but the disadvantage of being an invasive method. We suggest that the quality of the evidence should be improved and that an analysis of the impact of the imaging methods on patient treatment should be performed.
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http://dx.doi.org/10.1259/dmfr.25.5.9161176 | DOI Listing |
S Afr J Surg
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Division of Surgery, Tygerberg Hospital, Stellenbosch University, South Africa.
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Department of Surgery, School of Clinical Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, South Africa.
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January 2025
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Despite advances in multimodal cancer therapy, such as combining radical surgery with high-intensity chemoradiotherapy, for SMARCB1/INI-1-deficient sinonasal carcinoma (SDSC), the prognosis of patients remains poor. Immunotherapy is gaining increasing popularity as a novel treatment strategy for patients with SMARCB1/INI-1-deficient tumors. Herein, we report on the management of three patients with SDSC who received PD-1/PD-L1 inhibitor therapy as a part of multimodal therapy based on surgery and chemoradiotherapy.
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Department of Anesthesiology, Critical Care and Pain Medicine, UTHealth, Houston, Texas, USA.
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Aortic dissection is a life-threatening vascular emergency associated with high morbidity and mortality. Clinical manifestations might include severe chest pain to neurological deficits, depending on the arterial segments involved. Extensive dissections involving multiple aortic segments and branch vessel occlusions, such as the carotid arteries, are rare and pose unique diagnostic and therapeutic challenges.
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